암 환자 등의 식욕 상실 약물 요법 평가 페이지 정보 전성수 0 짧은주소 × 짧은 글주소 복사 Note! 위 주소를 클릭 후, 복사(Ctrl+C)하여 사용하세요. 이전글다음글 목록 본문 <TABLE style="BORDER-BOTTOM: medium none; BORDER-LEFT: medium none; BORDER-COLLAPSE: collapse; BORDER-TOP: medium none; BORDER-RIGHT: medium none; mso-yfti-tbllook: 1184; mso-padding-alt: 0cm 5.4pt 0cm 5.4pt" border=1 cellSpacing=0 cellPadding=0> <TBODY> <TR style="mso-yfti-irow: 0; mso-yfti-firstrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 461.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid; " width=615> <P style="TEXT-INDENT: 18pt; MARGIN: 0cm 0cm 0pt; " ><B ><SPAN style="COLOR: red; FONT-SIZE: 18pt">암 환자 등의 식욕 상실 약물 요법 평가</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 1; mso-yfti-lastrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 461.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=615> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN ><?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" /><FONT size=2> </FONT></SPAN></P></TD></TR></TBODY></TABLE> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <TABLE style="BORDER-BOTTOM: medium none; BORDER-LEFT: medium none; BORDER-COLLAPSE: collapse; BORDER-TOP: medium none; BORDER-RIGHT: medium none; mso-yfti-tbllook: 1184; mso-padding-alt: 0cm 5.4pt 0cm 5.4pt" border=1 cellSpacing=0 cellPadding=0> <TBODY> <TR style="HEIGHT: 31.9pt; mso-yfti-irow: 0; mso-yfti-firstrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 461.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; HEIGHT: 31.9pt; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid; " width=615> <P style="TEXT-INDENT: 16pt; MARGIN: 0cm 0cm 0pt; " ><B ><SPAN style="COLOR: #0000cc; FONT-SIZE: 16pt">왜 식욕 상실 증<SPAN >(Anorrexia)</SPAN>에 걸리는 가<SPAN ></SPAN></SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 1; mso-yfti-lastrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 461.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=615> <P style="TEXT-INDENT: -12pt; MARGIN: 0cm 0cm 0pt 12pt; " ><B ><SPAN style="COLOR: black; FONT-SIZE: 12pt; " >.1 </SPAN></B><B ><SPAN style="COLOR: black; FONT-SIZE: 12pt; ">암 환자등 만성 병에 걸리면<SPAN > </SPAN>전신적으로 대사 장애와 신체적 쇄약증으로<SPAN ><BR><SPAN > </SPAN></SPAN>인해 식욕을 상실하여 영양 불량 상태에 빠지게 된다 <SPAN ></SPAN></SPAN></B></P> <P style="TEXT-INDENT: -12pt; MARGIN: 0cm 0cm 0pt 12pt; " ><B ><SPAN style="COLOR: black; FONT-SIZE: 12pt; " > </SPAN></B></P> <P style="TEXT-INDENT: -24pt; MARGIN: 0cm 0cm 0pt 24pt; " ><B ><SPAN style="COLOR: black; FONT-SIZE: 12pt; " >.2 </SPAN></B><B ><SPAN style="COLOR: black; FONT-SIZE: 12pt; ">또한 <SPAN >, </SPAN>뇌하수체나<SPAN > </SPAN>갑상선<SPAN > </SPAN>기능 부전이나 수술<SPAN > </SPAN>후에나 수은<SPAN > </SPAN>등의<SPAN > </SPAN>만성<SPAN > </SPAN>중독 증<SPAN ></SPAN></SPAN></B></P> <P style="TEXT-INDENT: -12pt; MARGIN: 0cm 0cm 0pt 24pt; " ><B ><SPAN style="COLOR: black; FONT-SIZE: 12pt; ">이나 요로계의<SPAN > </SPAN>만성<SPAN > </SPAN>염증이나 십이지장 충<SPAN > </SPAN>등의<SPAN > </SPAN>기생충 감염에서도<SPAN > </SPAN></SPAN></B></P> <P style="TEXT-INDENT: 12pt; MARGIN: 0cm 0cm 0pt; " ><B ><SPAN style="COLOR: black; FONT-SIZE: 12pt; ">식욕 상실 증에 빠진다<SPAN ></SPAN></SPAN></B></P> <P style="TEXT-INDENT: 12pt; MARGIN: 0cm 0cm 0pt; " ><B ><SPAN style="COLOR: black; FONT-SIZE: 12pt; " ><SPAN > </SPAN></SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt" ><B ><SPAN style="COLOR: black; FONT-SIZE: 12pt; " >.3 </SPAN></B><B ><SPAN style="COLOR: black; FONT-SIZE: 12pt; ">이상과 같은 식욕 상실 증은 미각 이상을<SPAN > </SPAN>동반한<SPAN > </SPAN>식욕 상실이며<SPAN > </SPAN></SPAN></B></P> <P style="TEXT-INDENT: 12pt; MARGIN: 0cm 0cm 0pt; " ><B ><SPAN style="COLOR: black; FONT-SIZE: 12pt; ">영양 분<SPAN > </SPAN>섭취 량 감소<SPAN > </SPAN>이상으로<SPAN > </SPAN>현저하게<SPAN > </SPAN>여위고<SPAN > </SPAN>수척해진다<SPAN >.</SPAN></SPAN></B></P> <P style="TEXT-INDENT: 12pt; MARGIN: 0cm 0cm 0pt; " ><B ><SPAN style="COLOR: black; FONT-SIZE: 12pt; ">이러한 상태를 악액 질<SPAN >(Cachexia) </SPAN>이라고 하며 그 이유가 명확하게 <SPAN ></SPAN></SPAN></B></P> <P style="TEXT-INDENT: 12pt; MARGIN: 0cm 0cm 0pt; " ><B ><SPAN style="COLOR: black; FONT-SIZE: 12pt; ">밝혀지지 않했다<SPAN ></SPAN></SPAN></B></P> <P style="TEXT-INDENT: 12pt; MARGIN: 0cm 0cm 0pt; " ><B ><SPAN style="COLOR: black; FONT-SIZE: 12pt; " > </SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: black; FONT-SIZE: 12pt; " >.4</SPAN></B><B ><SPAN style="COLOR: black; FONT-SIZE: 12pt; ">이 같은 식욕 상실을 회복 시키기 위해 </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">영양 내용을 개선 시키거나<SPAN ></SPAN></SPAN></B></P> <P style="TEXT-INDENT: 12pt; MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">식이 카운 샐림으로는 개선 하기 어렵다 따라서 식욕을 촉진하고<SPAN ></SPAN></SPAN></B></P> <P style="TEXT-INDENT: 12pt; MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">체중을 증가 시켜 주는 약물 요법을 시도하게 된다 </SPAN></B></P></TD></TR></TBODY></TABLE> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <TABLE style="BORDER-BOTTOM: medium none; BORDER-LEFT: medium none; BORDER-COLLAPSE: collapse; BORDER-TOP: medium none; BORDER-RIGHT: medium none; mso-yfti-tbllook: 1184; mso-padding-alt: 0cm 5.4pt 0cm 5.4pt" border=1 cellSpacing=0 cellPadding=0> <TBODY> <TR style="mso-yfti-irow: 0; mso-yfti-firstrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 461.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid; " width=615> <P style="TEXT-INDENT: 16pt; MARGIN: 0cm 0cm 0pt; " ><B ><SPAN style="COLOR: #0000cc; FONT-SIZE: 16pt" ><SPAN > </SPAN></SPAN></B><B ><SPAN style="COLOR: #0000cc; FONT-SIZE: 16pt">식욕 상실 증 약물 요법 평가 </SPAN></B></P> <P style="TEXT-INDENT: 16pt; MARGIN: 0cm 0cm 0pt; " ><B ><SPAN style="COLOR: #0000cc; FONT-SIZE: 16pt"><SPAN ></SPAN></SPAN></B> </P></TD></TR> <TR style="HEIGHT: 516.9pt; mso-yfti-irow: 1; mso-yfti-lastrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 461.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; HEIGHT: 516.9pt; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=615> <P style="TEXT-INDENT: -10pt; MARGIN: 0cm 0cm 0pt 10pt; " align=left><SPAN ><FONT size=2>.</FONT></SPAN><SPAN style="FONT-SIZE: 12pt" >1 </SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">악화된 암 환자의 식욕 촉진 목적으로 </SPAN></B><B ><SPAN style="COLOR: #0000cc; FONT-SIZE: 12pt; " >Corticosteroid</SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">가 자주 사용되지만<SPAN ><BR></SPAN>체중 증가를 못 시킨다 효과가 일시적이고 장기 사용하면 부작용</SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-1"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">1-3</SPAN></SUP></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">이 있으므로 수명이 얼마 안 남은 환자</SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-4"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">4</SPAN></SUP></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">에게 단기 간 사용 한다<SPAN > </SPAN></SPAN></B></P> <P style="TEXT-INDENT: -12pt; MARGIN: 0cm 0cm 0pt 12pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B></P> <P style="TEXT-INDENT: -12pt; MARGIN: 0cm 0cm 0pt 12pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >.2 Progestogen</SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">계의</SPAN></B><B ><SPAN style="COLOR: #0000cc; FONT-SIZE: 12pt; " >Megestrol </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">은 무작위 이중 맹검 으로 밝혀진 바에 의하면 체중을<SPAN ><SPAN > </SPAN></SPAN>증가 시키지만 근육 살은 증가 안하고 지방 살 만 증가</SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-2"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">2</SPAN></SUP></B></A></SPAN><B ><SUP><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >,</SPAN></SUP></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-3"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">3</SPAN></SUP></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">시킨다<SPAN ></SPAN></SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt 12pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">그러나 오래 살 가능성 있는 환자</SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-4"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">4</SPAN></SUP></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">에게 일반적으로 투약 한다 <SPAN ></SPAN></SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt 12pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">같은 계열에 속한 </SPAN></B><B ><SPAN style="COLOR: #0000cc; FONT-SIZE: 12pt; " >Medroxyprogesterone.</SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-1"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">1</SPAN></SUP></B></A><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-6"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">6</SPAN></SUP></B></A></SPAN><B ><SUP><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></SUP></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " ><SPAN > </SPAN></SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">도 유사 효과를 지닌다<SPAN ></SPAN></SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >.3 Fluoxymesterone</SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-1"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">1</SPAN></SUP></B></A></SPAN><B ><SUP><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >,</SPAN></SUP></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-7"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">7</SPAN></SUP></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">과 같은<SPAN ><SPAN > </SPAN>Steroid</SPAN>계 단백 동화 호르몬제는<SPAN > Megestrol</SPAN></SPAN></B></P> <P style="TEXT-INDENT: 12pt; MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " ><SPAN > </SPAN>or Dexamethason</SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-8"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">8</SPAN></SUP></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">과 비교 해 보았으나 전자는 후자 보다 효과가 적다<SPAN ></SPAN></SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B></P> <P style="TEXT-INDENT: -12pt; MARGIN: 0cm 0cm 0pt 12pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >.4 </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">환자에 따라서는<SPAN ><SPAN > </SPAN></SPAN></SPAN></B><B ><SPAN style="COLOR: #0000cc; FONT-SIZE: 12pt; " >Metoclopramide</SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">같은 위장 운동 촉진 제를 사용하면 는 경우도 있다 왜냐 하면 이들의 식욕 상실은 위장 운동</SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-1"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">1</SPAN></SUP></B></A></SPAN><B ><SUP><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >,</SPAN></SUP></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-2"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">2</SPAN></SUP></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">이 감소 되므로 인해<SPAN > 2</SPAN>차적으로 나타난 것이기<SPAN >; </SPAN>때문이다 물론 구토 구역읕 완화</SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-6"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">6</SPAN></SUP></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">시킨다고 해서 반드시 식욕이 개선 된다고는 볼수 없다<SPAN ></SPAN></SPAN></B></P> <P style="TEXT-INDENT: -12pt; MARGIN: 0cm 0cm 0pt 12pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B></P> <P style="TEXT-INDENT: -12pt; MARGIN: 0cm 0cm 0pt 12pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >.5 </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">암 환자의 체중 감소를 유발하는 염증 유발<SPAN > Cytokine</SPAN>의 작용을<SPAN > NSAID</SPAN>가 억제 한다는 사실이 주장되어 왔다 해서 소수의 임상</SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-9"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">9</SPAN></SUP></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">이지만 <SPAN >Megestero </SPAN>에 </SPAN></B><B ><SPAN style="COLOR: #0000cc; FONT-SIZE: 12pt; " >Ibuprogen</SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">을 병용하면<SPAN > Megesterol</SPAN>의 작용이 향상된다는 보고가 있다<SPAN ></SPAN></SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >.6 </SPAN></B><B ><SPAN style="COLOR: #0000cc; FONT-SIZE: 12pt; " >Eicosapentanoic acid,(EPA) </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">가<SPAN ><SPAN > </SPAN></SPAN>근육 단백질 퇴화를 억제한다하여<SPAN > </SPAN></SPAN></B></P> <P style="TEXT-INDENT: 12pt; MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">사용해 보았으나 종합적 검토</SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-10"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">10</SPAN></SUP></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">결과 효과 입증이 불충분 하다<SPAN > </SPAN></SPAN></B></P> <P style="TEXT-INDENT: 12pt; MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">뿐만 아니라 효과를 나타내려면 고량 요법을 장기간 실시 해야하나<SPAN ></SPAN></SPAN></B></P> <P style="TEXT-INDENT: 12pt; MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">이에 대한 임상 자료가 불 충분하다<SPAN ></SPAN></SPAN></B></P> <P style="TEXT-INDENT: 10pt; MARGIN: 0cm 0cm 0pt; " align=left><SPAN ><FONT size=2> </FONT></SPAN></P></TD></TR></TBODY></TABLE><SPAN style="FONT-FAMILY: '맑은 고딕'; FONT-SIZE: 10pt; " ></SPAN> <P style="MARGIN: 0cm 0cm 0pt; " align=left><SPAN > </SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P> <TABLE style="BORDER-BOTTOM: medium none; BORDER-LEFT: medium none; BORDER-COLLAPSE: collapse; BORDER-TOP: medium none; BORDER-RIGHT: medium none; mso-yfti-tbllook: 1184; mso-padding-alt: 0cm 5.4pt 0cm 5.4pt" border=1 cellSpacing=0 cellPadding=0> <TBODY> <TR style="mso-yfti-irow: 0; mso-yfti-firstrow: yes; mso-yfti-lastrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 461.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid; " width=615> <P style="TEXT-INDENT: -12pt; MARGIN: 0cm 0cm 0pt 12pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >.7 Thalidomide </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">는 중증 췌장 암 환자의 체중 감소</SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-11"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">11</SPAN></SUP></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">완화 목적으로 처방 되지만 생활의 질 향상이 안 되고 생존 율 연장 효과가 현저하지 않다<SPAN > </SPAN></SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >.8 </SPAN></B><B ><SPAN style="COLOR: #0000cc; FONT-SIZE: 12pt; ">복합 처방으로 병용 요법</SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">도 연구 되어왔다<SPAN > Progestogen </SPAN>계의 <SPAN ></SPAN></SPAN></B></P> <P style="TEXT-INDENT: 24pt; MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >Medroxyprogesterone or Megestrol </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">과<SPAN > </SPAN></SPAN></B></P> <P style="TEXT-INDENT: 24pt; MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >Eicosapentaenoic acid(EPA) </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">와<SPAN > </SPAN></SPAN></B></P> <P style="TEXT-INDENT: 24pt; MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >Carnitine </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">과<SPAN > </SPAN></SPAN></B></P> <P style="TEXT-INDENT: 24pt; MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >Thalidomide </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">중에서<SPAN > 2</SPAN>종류 이상을 병용하거나<SPAN > 4 </SPAN>성분 모두를<SPAN > </SPAN></SPAN></B></P> <P style="TEXT-INDENT: 24pt; MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">복합 처밤 하는 경우<SPAN >, </SPAN>개별적으로는 효과가 없거나 경미하지만 <SPAN ></SPAN></SPAN></B></P> <P style="TEXT-INDENT: 24pt; MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">복합 한 처밤일 수록 현저한 효과</SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-12"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">12</SPAN></SUP></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">를 나타내었다<SPAN ></SPAN></SPAN></B></P> <P style="TEXT-INDENT: 24pt; MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">단<SPAN >,<SPAN > </SPAN>Cannabinoids, Cyproheptadine,<SPAN > </SPAN>Hydrazine.</SPAN></SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-1"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">1</SPAN></SUP></B></A></SPAN><B ><SUP><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >,</SPAN></SUP></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-2"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">2</SPAN></SUP></B></A></SPAN><B ><SUP><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >,</SPAN></SUP></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-6"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">6</SPAN></SUP></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">등을 병용 하는<SPAN > </SPAN></SPAN></B></P> <P style="TEXT-INDENT: 24pt; MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">경우는 별로 효과가 향상 되지 않는다<SPAN ></SPAN></SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >.9 </SPAN></B><B ><SPAN style="COLOR: #0000cc; FONT-SIZE: 12pt; ">에이즈 환자의</SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; "> 식욕 상실에<SPAN > Megestrol </SPAN>고량</SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-13"><SPAN style="COLOR: windowtext; TEXT-DECORATION: none; text-underline: none"><FONT size=2>13-15</FONT></SPAN></A><FONT size=2> </FONT></SPAN><FONT size=2>요법 </FONT><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; "><SPAN > </SPAN>과 <SPAN ></SPAN></SPAN></B></P> <P style="TEXT-INDENT: 24pt; MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >Oxandrolone</SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-16"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">16-19</SPAN></SUP></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">이 효과 적이다<SPAN ><SPAN > </SPAN></SPAN></SPAN></B></P> <P style="TEXT-INDENT: 24pt; MARGIN: 0cm 0cm 0pt; " align=left><B ><I style="mso-bidi-font-style: normal"><SPAN style="DISPLAY: none; COLOR: #333333; FONT-SIZE: 12pt; mso-hide: all" > </SPAN></I></B></P> <P style="MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >.10 </SPAN></B><B ><SPAN style="COLOR: #0000cc; FONT-SIZE: 12pt; ">투석</SPAN></B><SPAN style="COLOR: #0000cc" ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-20"><B ><SUP><SPAN style="COLOR: #0000cc; FONT-SIZE: 12pt; ">20</SPAN></SUP></B></A></SPAN><B ><SPAN style="COLOR: #0000cc; FONT-SIZE: 12pt; " > </SPAN></B><B ><SPAN style="COLOR: #0000cc; FONT-SIZE: 12pt; ">환자나</SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; "> 노인</SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-21"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">21</SPAN></SUP></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">들을 포함한 만성적 식욕 상실증에<SPAN > </SPAN></SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " ><SPAN > </SPAN></SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">대해서는 연구된 바가 별로 없다<SPAN > ,</SPAN></SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B></P> <P style="TEXT-INDENT: -12pt; MARGIN: 0cm 0cm 0pt 12pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >.11 </SPAN></B><B ><SPAN style="COLOR: #0000cc; FONT-SIZE: 12pt; ">노인들의 경우는</SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; "> 식욕 살실 약뮬 요법은 그 장단점이 갑론 을박이다<SPAN ></SPAN></SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt 12pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " ><SPAN > </SPAN><SPAN > </SPAN></SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">노인</SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-22"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">22</SPAN></SUP></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">에게<SPAN >; </SPAN>체중 감소를 치료 하기 위해<SPAN > Megestril</SPAN>을 사용한 경우 <SPAN ></SPAN></SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt 24pt; mso-para-margin-left: 2.4gd" align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">사망률이 증가한다는 한 건의 보고가 있으며 다른 보고<SPAN >.</SPAN></SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-23"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">23</SPAN></SUP></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">들은 유익하다는 점을 발표하였다<SPAN ></SPAN></SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >.12 </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">기타 연구 중의 약물로는 성장 호르몬</SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-19"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">19</SPAN></SUP></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > , </SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">내인성 호르몬<SPAN > Ghrelin</SPAN></SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/martindale/current/9063-s.htm#r9063-a3-8-m-24"><B ><SUP><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">24</SPAN></SUP></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > </SPAN></B></P> <P style="TEXT-INDENT: 18pt; MARGIN: 0cm 0cm 0pt; mso-char-indent-count: 1.5; " align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; ">선택 작용성<SPAN > Androgen </SPAN>수용체 조절 제 등이 있다<SPAN ></SPAN></SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt; " align=left><SPAN ><FONT size=2> </FONT></SPAN></P></TD></TR></TBODY></TABLE> <P style="MARGIN: 0cm 0cm 0pt" ><SPAN > </SPAN></P><SPAN style="FONT-FAMILY: '맑은 고딕'; FONT-SIZE: 10pt; " ></SPAN> <P style="MARGIN: 0cm 0cm 0pt; " align=left><SPAN > </SPAN></P> <TABLE style="BORDER-BOTTOM: medium none; BORDER-LEFT: medium none; BORDER-COLLAPSE: collapse; BORDER-TOP: medium none; BORDER-RIGHT: medium none; mso-yfti-tbllook: 1184; mso-padding-alt: 0cm 5.4pt 0cm 5.4pt" border=1 cellSpacing=0 cellPadding=0> <TBODY> <TR style="HEIGHT: 31.9pt; mso-yfti-irow: 0; mso-yfti-firstrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 461.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; HEIGHT: 31.9pt; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid; " width=615> <P style="TEXT-ALIGN: center; TEXT-INDENT: 16pt; MARGIN: 0cm 0cm 0pt; " align=center><B ><SPAN style="COLOR: #0000cc; FONT-SIZE: 16pt">근거<SPAN ></SPAN></SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 1; mso-yfti-lastrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 461.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=615> <P style="TEXT-INDENT: -18pt; MARGIN: 0cm 0cm 0pt 48pt; mso-list: l0 level1 lfo1; tab-stops: list 36.0pt" align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; mso-bidi-theme-font: minor-latin; " ><SPAN >1.<SPAN style="FONT: 7pt 'Times New Roman'"> </SPAN></SPAN></SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >1. Mantovani G, <I>et al.</I> </SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rfr_id=info:sid/medicinescomplete.com:www&rft.atitle=Managing%20cancer-related%20anorexia%2Fcachexia.&rft.stitle=Drugs&rft.date=2001&rft.volume=61&rft.pages=499-514&rft.au=Mantovani%20G%2C%20et%20al.&rft_id=info:pmid/11324680"><B ><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">Managing cancer-related anorexia/cachexia.</SPAN></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > <I>Drugs</I> 2001; <SPAN style="mso-bidi-font-weight: bold">61:</SPAN> 499–514. </SPAN></B><SPAN ><A title="Medline reference" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11324680&dopt=Abstract"><B ><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">PubMed</SPAN></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " ></SPAN></B></P> <P style="TEXT-INDENT: -18pt; MARGIN: 0cm 0cm 0pt 48pt; mso-list: l0 level1 lfo1; tab-stops: list 36.0pt" align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; mso-bidi-theme-font: minor-latin; " ><SPAN >2.<SPAN style="FONT: 7pt 'Times New Roman'"> </SPAN></SPAN></SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >2. Inui A. </SPAN></B><SPAN ><A href="http://www.medicinescomplete.com/mc/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rfr_id=info:sid/medicinescomplete.com:www&rft.atitle=Cancer%20anorexia-cachexia%20syndrome%3A%20current%20issues%20in%20research%20and%20management.&rft.stitle=CA%20Cancer%20J%20Clin&rft.date=2002&rft.volume=52&rft.pages=72-91&rft.au=Inui%20A&rft_id=info:pmid/11929007"><B ><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">Cancer anorexia-cachexia syndrome: current issues in research and management.</SPAN></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " > <I>CA Cancer J Clin</I> 2002; <SPAN style="mso-bidi-font-weight: bold">52:</SPAN> 72–91. </SPAN></B><SPAN ><A title="Medline reference" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11929007&dopt=Abstract"><B ><SPAN style="COLOR: blue; FONT-SIZE: 12pt; ">PubMed</SPAN></B></A></SPAN><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " ></SPAN></B></P> <P style="TEXT-INDENT: -18pt; MARGIN: 0cm 0cm 0pt 48pt; mso-list: l0 level1 lfo1; tab-stops: list 36.0pt" align=left><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; mso-bidi-theme-font: minor-latin; " ><SPAN >3.<SPAN style="FONT: 7pt 'Times New Roman'"> </SPAN></SPAN></SPAN></B><B ><SPAN style="COLOR: #333333; FONT-SIZE: 12pt; " >3. 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