류머티스 관절염 약 약효 비교 평가 페이지 정보 전성수 0 짧은주소 × 짧은 글주소 복사 Note! 위 주소를 클릭 후, 복사(Ctrl+C)하여 사용하세요. 이전글다음글 목록 본문 <TABLE class=tbl2> <TBODY> <TR style="mso-yfti-irow: 0; mso-yfti-firstrow: yes"> <TD class=tbl2-title> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 20pt">류머티스 관절염 약 약효 비교 평가</SPAN></B></P></TD></TR> <TR style="HEIGHT: 35.15pt; mso-yfti-irow: 1; mso-yfti-lastrow: yes"> <TD class=tbl2-contents> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">류머티스 관절염에 사용되는<SPAN> Etanercept</SPAN>는</SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">매우 값비싼 유전공학제품이다</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">류머티스 관절염에 사용되어온</SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">부신 피질 호로몬제 보다 수 백 배 더 비싸다 </SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">그러나 류머티스 관절염에 대한 치료 효과는 </SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">두 약물이 동일한 효과를 나타낸다는 사실이 밝혀졌다</SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">더구나 약을 중단 후의 약효는 </SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">부신 피질 호르몬제가<SPAN> Etanercept </SPAN>보다 </SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">훨씬 더 지속적이고 더 강력하다는 사실이 밝혀졌다</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">Etanercept</SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">는 관절을 파괴시키는 </SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">여러 가지 염증 유발 인자 중 <SPAN>TNF-</SPAN>α 하나만을 무력화시키는 약이다</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="FONT-SIZE: 14pt">부신 피질 호르몬제는<SPAN> TNF-</SPAN>α 뿐 아니라 </SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="FONT-SIZE: 14pt">모든 염증 유발 인자를 종합적으로 억제할 수 </SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="FONT-SIZE: 14pt">있는 약임은 주지의 사실인 것이다</SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt"><BR>이는 프랑스<SPAN> Nice </SPAN>의대 연구팀의 연구결과이며</SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">류머티스학회지를 통해 발표된 내용이다 </SPAN><SPAN style="FONT-FAMILY: '맑은 고딕'; COLOR: black; FONT-SIZE: 14pt"> </SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="FONT-FAMILY: '맑은 고딕'; COLOR: black; FONT-SIZE: 14pt"></P> <P><IMG src="/_dimg/1%20염증%20인자.bmp"></P></SPAN></B> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"> [</SPAN></B><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">그림<SPAN>] </SPAN>관절을 파괴시키는 염증 유발 물질은<SPAN> TNF-</SPAN>α 이외에도 여러가지가</SPAN></B></P> <P style="TEXT-INDENT: -56pt; MARGIN: 0cm 0cm 0pt 56pt; mso-char-indent-count: -4.0" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"><SPAN> </SPAN></SPAN></B><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">관절에 염증을 유발한다<SPAN>.<SPAN> </SPAN>Etanercept</SPAN>는<SPAN> TNF-</SPAN>α 한가지만을 억제하지만신 피질 호르몬은 모든 염증 유발 인자를 억제한다</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 0; mso-yfti-firstrow: yes"> <TD class=tbl2-subtitle> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: blue; FONT-SIZE: 20pt">류머티스 단일 관절염 환자를 대상으로 비교 </SPAN></B></P></TD></TR> <TR style="HEIGHT: 35.15pt; mso-yfti-irow: 1; mso-yfti-lastrow: yes"> <TD class=tbl2-contents> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">본 임상은 약효 비교를 정확하게 할 수 있도록 하기 위하여</SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">아래 표에서와 같이</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"> </SPAN></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt"><BR>관절 한 곳에만 류머티스 관절염 병태를 지닌</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"><BR></SPAN><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">이른바 단일 관절염<SPAN>(Mono-arthritis) </SPAN>환자만을 대상으로 했다</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <TABLE style="BORDER-BOTTOM: medium none; BORDER-LEFT: medium none; BORDER-COLLAPSE: collapse; BORDER-TOP: medium none; BORDER-RIGHT: medium none; mso-yfti-tbllook: 1184" border=1 cellSpacing=0 cellPadding=0 table> <TBODY> <TR style="mso-yfti-irow: 0; mso-yfti-firstrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 118.8pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=158 colSpan=2> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=180> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">Etanercept </SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">정맥 주사 군 </SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=208> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">Betamethasone</SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">관절 내 주사 군</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 118.8pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #f2f2f2; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=158 colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center> </P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #f2f2f2; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">1 ml (25mg)</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #f2f2f2; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=208> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">1ml(4mg)</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 118.8pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=158 colSpan=2> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">나이 </SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">58</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=208> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">59.5</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 118.8pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=158 colSpan=2> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">단일 관절염 </SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center> </P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=208> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center> </P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 47.95pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=64> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 70.85pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=94> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">무릎</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">4</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=208> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">7</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 47.95pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=64> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 70.85pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=94> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">발목</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">2</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=208> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">2</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 47.95pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=64> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 70.85pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=94> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">팔목</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">9</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=208> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">5</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 47.95pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=64> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 70.85pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=94> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">팔꿈치</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">2</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=208> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">3</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 118.8pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=158 colSpan=2> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">투약 기간 </SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">3</SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">개월</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=208> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">4 </SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">주</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 118.8pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #f2f2f2; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=158 colSpan=2> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">관찰 </SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 290.6pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #f2f2f2; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=387 colSpan=2> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">1</SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">주<SPAN> 2</SPAN>주<SPAN> 4</SPAN>주<SPAN> 8</SPAN>주<SPAN> 16</SPAN>주<SPAN> 24</SPAN>주</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 10; mso-yfti-lastrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 118.8pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=158 colSpan=2> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">관찰 내용</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 290.6pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=387 colSpan=2> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">-</SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">관절 통증 </SPAN></B></P> <P style="LINE-HEIGHT: 150%; TEXT-INDENT: 14pt; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">(VAS </SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">점수<SPAN>: Visual Analog Score)</SPAN></SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">-</SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">관절 병태 관찰<SPAN>(DAS28)</SPAN></SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">-</SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">관절 부종 </SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">-</SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">일상 활동 내용 분석<SPAN>(HAQ)</SPAN></SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">-</SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">적혈구 침강 속도<SPAN>(ESR): </SPAN>염증 강도 </SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">-C-</SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">반응성 단백<SPAN>(</SPAN>염증 유발 단백<SPAN>)</SPAN></SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">-</SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">관절 둘레 </SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">-</SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">부작용</SPAN></B></P></TD></TR></TBODY></TABLE> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left></P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"></SPAN></B> </P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"></SPAN></B> </P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"><IMG src="/_dimg/2%20관절.bmp"></SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">[</SPAN></B><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">그림<SPAN>] </SPAN>류머티스 관절염 병태가 개선되는 것을 측정하려면</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"><SPAN> </SPAN></SPAN></B><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">병태 개선 점수<SPAN>(DAS) </SPAN>와 염증 개선 점수<SPAN>(ESR) </SPAN>과 </SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"><SPAN> </SPAN></SPAN></B><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">일상 생활 가능 정도 등을 채점하여 평가한다</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left></P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"></SPAN></B> </P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"></SPAN></B> </P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"></SPAN></B> </P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"><IMG src="/_dimg/3%20침강.bmp"></SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">[</SPAN></B><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">그림<SPAN>] </SPAN>염증이 발생하면 적혈구 침강 속도가 빨라진다 이를 측정하여</SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"><SPAN> </SPAN></SPAN></B><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">염증 개선도를 평가한다</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" align=left></P> <P style="MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"> <P style="MARGIN: 0cm 0cm 0pt" align=left><BR> </P> <P style="MARGIN: 0cm 0cm 0pt" align=left><IMG src="/_dimg/4%20판누스.bmp"><BR>[</SPAN></B><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">그림<SPAN>] </SPAN>관절과 관절을 잇고있는 활액낭이 파괴되면서 염증을 이르키는 것이</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"> </SPAN></B><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">류머티스 관절염이다<SPAN>. </SPAN>염증 부위는 판누스<SPAN>(Pannus)</SPAN>라 한다</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"></SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"></SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"></SPAN></B> </P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"></SPAN></B> </P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"></SPAN></B> </P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"><IMG src="/_dimg/5%20돌기.bmp"></SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">[</SPAN></B><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">그림<SPAN>] </SPAN>활액낭이 파괴되면서 염증을 이르키는 곳 판누스<SPAN> (Pannus)</SPAN>는 </SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"> </SPAN></B><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">돌기같은 것이 생겨 연골을 파괴한다</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" align=left> </P> <P style="MARGIN: 0cm 0cm 0pt" align=left> </P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt"><IMG src="/_dimg/6%20집중부.bmp"> </SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">[</SPAN></B><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">그림<SPAN>] </SPAN>류마티스 관절의 염증 부위 판누스<SPAN> (Pannus)</SPAN>는 </SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"> </SPAN></B><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">모든 염증 인자와 항염인자가 집결하여 대결하는 곳이다</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"> </SPAN></B><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">약물은 이곳에 직접 작용해야 약효가 빠르다</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 0; mso-yfti-firstrow: yes; mso-yfti-lastrow: yes"> <TD class=tbl2-subtitle> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: blue; FONT-SIZE: 20pt">투약<SPAN> 4</SPAN>주째의 약효는 두 약물 다 우수하지만</SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: blue; FONT-SIZE: 20pt"></SPAN></B> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: blue; FONT-SIZE: 20pt">염증 억제력은 부신 피질 호르몬이 더 우수</SPAN></B></P></TD></TR> <TR style="HEIGHT: 35.15pt; mso-yfti-irow: 0; mso-yfti-firstrow: yes; mso-yfti-lastrow: yes"> <TD class=tbl2-contents> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">투약 후<SPAN> 4</SPAN>주째의 약효는</SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">아래 표에서와 같이 </SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">두 약물이 모두 우수한 약효를 발휘하고 있다</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">부신피질 호르몬이 약간은 더 좋으나 두 약물 간에 차이가 별로 없다</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <TABLE style="BORDER-BOTTOM: medium none; BORDER-LEFT: medium none; BORDER-COLLAPSE: collapse; BORDER-TOP: medium none; BORDER-RIGHT: medium none; mso-yfti-tbllook: 1184" border=1 cellSpacing=0 cellPadding=0 table> <TBODY> <TR style="mso-yfti-irow: 0; mso-yfti-firstrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 147.15pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=196> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">통증 등<SPAN> VAS</SPAN>점수</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">Etanercept </SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 163pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=217> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">Betamethasone</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 147.15pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=196> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">투약 전 </SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">65.8</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 163pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=217> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">59.5</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 147.15pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=196> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">투약 후<SPAN> 4</SPAN>주 째</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">39.1</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 163pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=217> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">36.3</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 3; mso-yfti-lastrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 444.85pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ff99ff; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=593 colSpan=3> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">점수 적을수록 우수 </SPAN></B></P></TD></TR></TBODY></TABLE> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P> <TABLE style="BORDER-BOTTOM: medium none; BORDER-LEFT: medium none; BORDER-COLLAPSE: collapse; BORDER-TOP: medium none; BORDER-RIGHT: medium none; mso-yfti-tbllook: 1184" border=1 cellSpacing=0 cellPadding=0 table> <TBODY> <TR style="mso-yfti-irow: 0; mso-yfti-firstrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 157.5pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=210> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">병태 점수<SPAN>(DA28)</SPAN></SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 145.5pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=194> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">Etanercept </SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 173.25pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=231 colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">Betamethasone</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 157.5pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=210> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">투약 전 </SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 145.5pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=194> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">4.6</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 173.25pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=231 colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">3.7</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 157.5pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=210> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">투약 후<SPAN> 4</SPAN>주 째</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 145.5pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=194> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">4.1</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 173.25pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=231 colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">3.6</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 3; mso-yfti-lastrow: yes; mso-row-margin-right: 31.4pt"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 444.85pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ff99ff; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=593 colSpan=3> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">점수 적을수록 우수 </SPAN></B></P></TD> <TD style="BORDER-BOTTOM: #ffffff; BORDER-LEFT: #ffffff; BACKGROUND-COLOR: transparent; PADDING-LEFT: 0cm; PADDING-RIGHT: 0cm; BORDER-TOP: #ffffff; BORDER-RIGHT: #ffffff" width=42> <P style="MARGIN: 0cm 0cm 0pt"> </P></TD></TR> <TR> <TD style="BORDER-BOTTOM: #ffffff; BORDER-LEFT: #ffffff; BACKGROUND-COLOR: transparent; BORDER-TOP: #ffffff; BORDER-RIGHT: #ffffff" width=210></TD> <TD style="BORDER-BOTTOM: #ffffff; BORDER-LEFT: #ffffff; BACKGROUND-COLOR: transparent; BORDER-TOP: #ffffff; BORDER-RIGHT: #ffffff" width=194></TD> <TD style="BORDER-BOTTOM: #ffffff; BORDER-LEFT: #ffffff; BACKGROUND-COLOR: transparent; BORDER-TOP: #ffffff; BORDER-RIGHT: #ffffff" width=189></TD> <TD style="BORDER-BOTTOM: #ffffff; BORDER-LEFT: #ffffff; BACKGROUND-COLOR: transparent; BORDER-TOP: #ffffff; BORDER-RIGHT: #ffffff" width=42></TD></TR></TBODY></TABLE> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P> <TABLE style="BORDER-BOTTOM: medium none; BORDER-LEFT: medium none; BORDER-COLLAPSE: collapse; BORDER-TOP: medium none; BORDER-RIGHT: medium none; mso-yfti-tbllook: 1184" border=1 cellSpacing=0 cellPadding=0 table> <TBODY> <TR style="mso-yfti-irow: 0; mso-yfti-firstrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 147.15pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=196> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">활액낭 두께</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">Etanercept </SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 163pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=217> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">Betamethasone</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 147.15pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=196> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">투약 전 </SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">9.1</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 163pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=217> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">7.1</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 147.15pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=196> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">투약 후<SPAN> 4</SPAN>주 째</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">8.3</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 163pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=217> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">6.0</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 3; mso-yfti-lastrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 444.85pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ff99ff; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=593 colSpan=3> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">점수 적을수록 우수 </SPAN></B></P></TD></TR></TBODY></TABLE> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">그러나 아래표에서 처럼 적혈구 침강 속도로 나타나는 </SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">염증 상태 억제 효과에 대해서는 </SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt"><BR></SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">부신피질이<SPAN> 4</SPAN>주째부터 월등하게 우수하다</SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P> <TABLE style="BORDER-BOTTOM: medium none; BORDER-LEFT: medium none; BORDER-COLLAPSE: collapse; BORDER-TOP: medium none; BORDER-RIGHT: medium none; mso-yfti-tbllook: 1184" border=1 cellSpacing=0 cellPadding=0 table> <TBODY> <TR style="mso-yfti-irow: 0; mso-yfti-firstrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 147.15pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=196> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">적혈구 침강<SPAN> ESR<BR>(</SPAN>전반적 염증 지수<SPAN>)</SPAN></SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">Etanercept </SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 163pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=217> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">Betamethasone</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 147.15pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=196> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">투약 전 </SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">32.1</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 163pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=217> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">25.6</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 147.15pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=196> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">투약 후<SPAN> 4</SPAN>주 째</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">32.1</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 163pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=217> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">19.5</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 3; mso-yfti-lastrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 444.85pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ff99ff; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=593 colSpan=3> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">점수 적을수록 우수 </SPAN></B></P></TD></TR></TBODY></TABLE> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"><BR><IMG src="/_dimg/8%20주쇼ㅏ.bmp"></SPAN></B></P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">[</SPAN></B><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">그림<SPAN>] </SPAN>부신 피질은 관절에 직접 주사하는 것이 매우 효과적이다</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"><SPAN> </SPAN></SPAN></B><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">본 임상에서는<SPAN> 4</SPAN>주간 주사하고 중단하면 그 개선 효과가 </SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: red; FONT-SIZE: 14pt"><SPAN> </SPAN>24</SPAN></B><B><SPAN style="COLOR: red; FONT-SIZE: 14pt">주간 지속되었다</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 0; mso-yfti-firstrow: yes"> <TD class=tbl2-subtitle> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: blue; FONT-SIZE: 20pt">24</SPAN></B><B><SPAN style="COLOR: blue; FONT-SIZE: 20pt">주째의 관절 병태 개선도</SPAN></B><B><SPAN style="COLOR: blue; FONT-SIZE: 20pt">부신 피질이 매우 우수</SPAN></B></P></TD></TR> <TR style="HEIGHT: 35.15pt; mso-yfti-irow: 1; mso-yfti-lastrow: yes"> <TD class=tbl2-contents> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">부신 피질 호르몬 제는<SPAN> 4</SPAN>주간 투약하고 중단했으며</SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">Etanercept</SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">는<SPAN> 12</SPAN>주간 투약하고 중단 했다</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">두 약의<SPAN> 4</SPAN>주째의 약효는 아래 표에서와 같이 <SPAN>24</SPAN>주째에도 지속되었다</SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt"><BR>그러나<SPAN> 24</SPAN>주째의 병태 개선<SPAN> (DAS28) </SPAN>점수는</SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">부신 피질 호르몬제가<SPAN> Etnercept </SPAN>보다 훨씬 우수함이 들어났다</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt"><BR>아래 표는 통증 등<SPAN>(VAS</SPAN>점수<SPAN>)</SPAN>의 변화를 나타내고 있는바</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P><SPAN style="COLOR: black; FONT-SIZE: 14pt"> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><BR><B><SPAN>24</SPAN></B> </SPAN><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">주째는 약물이 중단된 상태이므로</SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"><B><SPAN>4</SPAN></B></SPAN><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">주째 보다<SPAN> 24</SPAN>주째에 약간 통증이 증가했으나 </SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P><SPAN style="COLOR: black; FONT-SIZE: 14pt"> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><BR></SPAN><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">투약 전 보다는 현저히 개선된 상태이다</SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P> <TABLE style="BORDER-BOTTOM: medium none; BORDER-LEFT: medium none; BORDER-COLLAPSE: collapse; BORDER-TOP: medium none; BORDER-RIGHT: medium none; mso-yfti-tbllook: 1184" border=1 cellSpacing=0 cellPadding=0 table> <TBODY> <TR style="mso-yfti-irow: 0; mso-yfti-firstrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 147.15pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=196> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">통증 등<SPAN> VAS</SPAN>점수</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">Etanercept </SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 163pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=217> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">Betamethasone</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 147.15pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=196> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">투약 전 </SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">65.8</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 163pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=217> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">59.5</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 147.15pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=196> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">4</SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">주 째</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">39.1</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 163pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=217> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">36.3</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 147.15pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=196> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">24</SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">주 째</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">41.1</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 163pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=217> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">40.1</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 4; mso-yfti-lastrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 444.85pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ff99ff; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=593 colSpan=3> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">점수 적을수록 우수 </SPAN></B></P></TD></TR></TBODY></TABLE> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt"><BR>아래 표는 병태<SPAN>(DAS28)</SPAN>의 변화를 나타내고 있는바</SPAN></B></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"><B><SPAN>24</SPAN></B></SPAN><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">주째는 약물이 중단된 상태임에도 불구하고</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"><B><SPAN>4</SPAN></B></SPAN><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">주째보다<SPAN> 24</SPAN>주째에도 개선되었다</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left> </P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">그러나 놀랍게도 부신 피질 호르몬의 효과가 <SPAN>Etanercept</SPAN>보다 훨씬 우수하다</SPAN></B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></P> <P style="LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=left><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN> </P> <TABLE style="BORDER-BOTTOM: medium none; BORDER-LEFT: medium none; BORDER-COLLAPSE: collapse; BORDER-TOP: medium none; BORDER-RIGHT: medium none; mso-yfti-tbllook: 1184" border=1 cellSpacing=0 cellPadding=0 table> <TBODY> <TR style="mso-yfti-irow: 0; mso-yfti-firstrow: yes"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 147.15pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=196> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">병태 점수<SPAN>(DA28)</SPAN></SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">Etanercept </SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 163pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=217> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">Betamethasone</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 147.15pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=196> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">투약 전 </SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">4.6</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 163pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=217> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">3.7</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 147.15pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=196> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt"> 4</SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">주 째</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 134.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" width=180> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 150%; MARGIN: 0cm 0cm 0pt" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">4.1</SPAN></B></P></ 이전글다음글 목록
