부신 피질 호르몬제 부작용인 골다공증의 특징과 병용해야 할 처방? 페이지 정보 전성수 0 짧은주소 × 짧은 글주소 복사 Note! 위 주소를 클릭 후, 복사(Ctrl+C)하여 사용하세요. 이전글다음글 목록 본문 <P> <TABLE style="BORDER-BOTTOM: medium none; BORDER-LEFT: medium none; BORDER-COLLAPSE: collapse; BORDER-TOP: medium none; BORDER-RIGHT: medium none" border=1 cellSpacing=0 cellPadding=0 width=789> <TBODY> <TR style="HEIGHT: 42.25pt"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #92cddc; HEIGHT: 42.25pt; VERTICAL-ALIGN: middle; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" width=789 colSpan=5> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 250%; FONT-SIZE: 20pt"><B>부신 피질 호르몬제 부작용인</P> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 250%; FONT-SIZE: 20pt"><B>골다공증의 특징과 병용해야 할 처방?</P></B></B></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #daeef3; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=170> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 14pt">2차성 골다공증</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=610 colSpan=4> <P style="LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 12pt"><FONT size=4>부신피질 호르몬제 부작용인 골다공증을 </FONT></SPAN></B></P> <P style="LINE-HEIGHT: 300%"><FONT size=4><B><SPAN style="FONT-SIZE: 12pt">2</SPAN></B><B><SPAN style="FONT-SIZE: 12pt">차성 골다공증이라 한다.</SPAN></B></FONT></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #daeef3; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=170> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 14pt">위험군</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=610 colSpan=4> <P style="LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 12pt"></SPAN></B> </P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #daeef3; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=170> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 14pt">발생 빈도</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=610 colSpan=4> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: #333333; FONT-SIZE: 12pt">장기 복용자의<SPAN> 30%-50% </SPAN>에게서 발생</SPAN></B><B><SPAN style="FONT-SIZE: 12pt"></SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #daeef3; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=170> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 14pt">초기 골절 부위</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=610 colSpan=4> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">해면체 많은 척추 및 히프 골절이 가장 먼저 나타남</SPAN></B></P> <P style="LINE-HEIGHT: 300%; TEXT-INDENT: 12pt"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">척추 골절자 <SPAN>------- 17.7</SPAN>배</SPAN></B></P> <P style="LINE-HEIGHT: 300%; TEXT-INDENT: 12pt"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">히프 골절자 <SPAN>------- 7 </SPAN>배</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #daeef3; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=170> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 14pt">2상성 유발</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=610 colSpan=4> <P style="LINE-HEIGHT: 300%; TEXT-INDENT: -18pt; MARGIN: 0cm 0cm 0pt 38pt"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt"><SPAN>1)<SPAN style="FONT: 7pt 'Times New Roman'"> </SPAN></SPAN>첫 년도에 골<SPAN> 6~12% </SPAN>소실</SPAN></B></P> <P style="LINE-HEIGHT: 300%; MARGIN: 0cm 0cm 0pt 38pt"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">그러나 복용 시작 <SPAN>3</SPAN>개월 동안<SPAN> 75% </SPAN>소실 <SPAN><SPAN> </SPAN></SPAN></SPAN></B></P> <P style="LINE-HEIGHT: 300%; TEXT-INDENT: -18pt; MARGIN: 0cm 0cm 0pt 38pt"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt"><SPAN>2)<SPAN style="FONT: 7pt 'Times New Roman'"> </SPAN></SPAN>2차년도부터 매년 <SPAN>3% </SPAN>씩 소실</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #daeef3; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" rowSpan=7 width=170> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 14pt">Steroid 골절 </SPAN></B></P> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 14pt">위험은 </SPAN></B></P> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 14pt">용량 불문 </SPAN></B></P> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 14pt">기간 불문 </SPAN></B></P> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 14pt">제형 불문</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=610 colSpan=4> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">- 소량에서도 나타남 </SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #c2d69b; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" width=150> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">Prednisolone</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" width=460 colSpan=3> <P style="LINE-HEIGHT: 300%" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">1일<SPAN> 2.5~7.5mg</SPAN></SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #c2d69b; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" rowSpan=2 width=150> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">대응량</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccc0d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" width=350 colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">Prednisone</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid"> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">3.1~9.3mg</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccc0d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" width=350 colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">Dexamethasone</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid"> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">0.35mg~1.05mg</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=610 colSpan=4> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">- Steroid 흡입자</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=610 colSpan=4> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">- 2일에 한번 씩 투약하는 경우</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=610 colSpan=4> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">- 간헐적 복용자에게도 나타남</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #daeef3; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" rowSpan=6 width=170> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 14pt">steroid 처방자중 </SPAN></B></P> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 14pt">위험군</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" width=150> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">나이</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" width=460 colSpan=3> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">- 60-80세 노인</SPAN></B></P> <P style="LINE-HEIGHT: 300%; TEXT-INDENT: 6pt"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">18-60세 층에 비하여 </SPAN></B></P> <P style="LINE-HEIGHT: 300%; TEXT-INDENT: 6pt"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">척추 골절이<SPAN> 26</SPAN>배</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" width=150> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">비만도</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" width=460 colSpan=3> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">- 24이하</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" width=150> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">기호</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" width=460 colSpan=3> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">- 담배 및 과음 </SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" width=150> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">병력</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" width=460 colSpan=3> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">- 류머티스 관절염</SPAN></B></P> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">- 대장 질환 <SPAN>(</SPAN>궤양성 질환<SPAN>)</SPAN></SPAN></B></P> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">- 스테로이드 활성화 효소<SPAN>(11β-HSD1) </SPAN>증가자</SPAN></B></P> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">- 결절 경험자 </SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" width=150> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt"></SPAN></B> </P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" width=460 colSpan=3> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">** 11β-HSD1 : Cortisone 및 <SPAN>Prednison </SPAN>같은 불활성<SPAN> steroid </SPAN>를 <SPAN>Cortisol, Prednisolone </SPAN>같은 활성<SPAN>Steroid </SPAN>로 전환시키는 효소 <SPAN>(</SPAN>나이들수록 증가<SPAN>)</SPAN></SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" width=150> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">남녀</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" width=460 colSpan=3> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">- 공통적<SPAN> (</SPAN>민족간 차이 없음<SPAN>)</SPAN></SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #daeef3; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" rowSpan=9 width=170> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 14pt">병태 특징</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=610 colSpan=4> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">- 갱년기 여인의 골다공증과 골절 병태가 전혀 다르다.</SPAN></B></P></TD></TR> <TR> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=150> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">Steroid 는 직접적으로</SPAN></B></P> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">뼈를 파괴</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=460 colSpan=3> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">- 골밀도 감소 전에 골강도 감소<SPAN><SPAN> </SPAN></SPAN></SPAN></B></P> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">(뼈의 초기 세포인 골아세포의 자살 때문<SPAN>)</SPAN></SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 21"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=150> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">조골세포 감소</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=460 colSpan=3> <P style="LINE-HEIGHT: 300%; TEXT-INDENT: -12pt; MARGIN: 0cm 0cm 0pt 12pt"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">- 새 뼈를 생성시키는 조골세포<SPAN>(Osteoblast) </SPAN>수를 감소</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 22"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=610 colSpan=4> <P style="LINE-HEIGHT: 300%; TEXT-INDENT: -36pt; MARGIN: 0cm 0cm 0pt 36pt" align=center><B><SPAN style="COLOR: red; FONT-SIZE: 12pt"><img src="http://holytree.co.kr/_dimg/뼈1.jpg" alt=""/></SPAN></B></P> <P style="LINE-HEIGHT: 300%; TEXT-INDENT: -36pt; MARGIN: 0cm 0cm 0pt 36pt"><B><SPAN style="COLOR: red; FONT-SIZE: 12pt">[</SPAN></B><B><SPAN style="COLOR: red; FONT-SIZE: 12pt">그림<SPAN>] </SPAN>뼈는 파괴와 생성을 반복<SPAN>, </SPAN>오래된 뼈는 파골세포 <SPAN>(Osteoclast)</SPAN>가 파괴시키고 이 자리에 조골세포<SPAN>(Osteoblast)</SPAN>가 새 뼈를 만듦.</SPAN></B></P> <P style="LINE-HEIGHT: 300%; MARGIN: 0cm 0cm 0pt 36pt; mso-para-margin-left: 3.6gd"><B><SPAN style="COLOR: red; FONT-SIZE: 12pt">파골세포가 조골세포보다 많은 경우 골다공증에 걸림.</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 23"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=150> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">파골세포 감소</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=460 colSpan=3> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">오래된 뼈를 파괴시켜 새 뼈의 터전을 만드는 파골세포<SPAN>(Osteoclast) </SPAN>생성을 감소시키면서 수명은 조골세포 보다 오래 존재하게 하여 뼈의 생성을 억제</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 24"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" rowSpan=2 width=150> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">혈관 재생 인자</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=460 colSpan=3> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">- 뼈 속 혈관 재생 인자<SPAN>(VEGF) </SPAN>감소</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 25"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=460 colSpan=3> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">- 골격근 혈관 재생 감소</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 26"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=150> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">골 퇴화</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=460 colSpan=3> <P style="LINE-HEIGHT: 300%; TEXT-INDENT: -12pt; MARGIN: 0cm 0cm 0pt 12pt"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">- 지방 성분으로 된 황색 골수의 지방이 혈관 속으로 들어가 여러 장기에 분포한 혈관에 지방 색전증을 야기</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 27"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=610 colSpan=4> <P style="LINE-HEIGHT: 300%" align=center><B><SPAN style="COLOR: black; FONT-SIZE: 12pt"> <IMG style="WIDTH: 315px; HEIGHT: 335px" src="/_dimg/뼈2.jpg" width=394 height=422></SPAN></B></P> <P style="LINE-HEIGHT: 300%; TEXT-INDENT: -36pt; MARGIN: 0cm 0cm 0pt 36pt"><B><SPAN style="COLOR: red; FONT-SIZE: 12pt">[</SPAN></B><B><SPAN style="COLOR: red; FONT-SIZE: 12pt">그림<SPAN>] </SPAN>부신피질 호르몬에 의한 골다공증은 </SPAN></B></P> <P style="LINE-HEIGHT: 300%; MARGIN: 0cm 0cm 0pt 36pt; mso-para-margin-left: 3.6gd"><B><SPAN style="COLOR: red; FONT-SIZE: 12pt">골밀도가 감소하기 전 골생성 세포<SPAN>(Osteocyte)</SPAN>가 사멸되면서 뼈의 강도가 먼저 약화된다.</SPAN></B></P> <P style="LINE-HEIGHT: 300%; TEXT-INDENT: 36pt; mso-char-indent-count: 3.0"><B><SPAN style="COLOR: red; FONT-SIZE: 12pt">즉 골밀도와 골절은 비례하지 않는다.</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 28"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #daeef3; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" rowSpan=7 width=170> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 14pt">Steroid</SPAN></B></P> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 14pt">처방시</SPAN></B></P> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 14pt">환자에게</SPAN></B></P> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 14pt">알려야 할</SPAN></B></P> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 14pt">Steroid 의</SPAN></B></P> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="FONT-SIZE: 14pt">부작용</SPAN></B><B><SPAN style="FONT-SIZE: 12pt"></SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=610 colSpan=4> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">부작용</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 29"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=350 colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">골절</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">체중 증가</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 30"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=350 colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">녹내장</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">부종</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 31"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=350 colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">백내장</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">멍이 잘 듦</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 32"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=350 colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">혈당 상승</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">청각 장애</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 33"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=350 colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">혈압 상승</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">근육 통증</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 34"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=350 colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">고지혈증</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">부신 부전</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 35"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #daeef3; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=170> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">간이 골다공증 진단</SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 14pt"></SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=610 colSpan=4> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">- 키가 줄어들면 척추 골절 진단 </SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 36"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=789 colSpan=5> <P style="LINE-HEIGHT: 300%" align=center><B><SPAN style="FONT-SIZE: 14pt">골절 예방용 처방<SPAN><SPAN> </SPAN></SPAN></SPAN></B><B><SPAN style="COLOR: #333333; FONT-SIZE: 14pt"></SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 37"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #daeef3; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=157> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%; TEXT-INDENT: -14pt; MARGIN: 0cm 0cm 0pt 14pt"><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">대상자 예</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=610 colSpan=4> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">- Prednisolone 1일<SPAN> 10mg~20mg 2</SPAN>년간 투약자</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 38"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #daeef3; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" rowSpan=5 width=157> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">처방</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" width=500 colSpan=3> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">Bisphosphonate drug</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" rowSpan=5> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">2년간</SPAN></B></P> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">병용 투약</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 39"> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid"> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">Alendronate</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">1주<SPAN> 1</SPAN>회<SPAN> 1</SPAN>회<SPAN> 70mg</SPAN></SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 40"> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid"> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">or zoledronic acid</SPAN></B></P> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">(zoledronate)</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">1년<SPAN> 1</SPAN>회</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 41"> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #b6dde8; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid"> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%; TEXT-INDENT: -12pt; MARGIN: 0cm 0cm 0pt 12pt"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">비타민<SPAN>-D3</SPAN></SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">1일<SPAN> 2,000 IU</SPAN></SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 42"> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #b6dde8; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid"> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%; TEXT-INDENT: -12pt; MARGIN: 0cm 0cm 0pt 12pt"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">칼슘</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" colSpan=2> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">1일<SPAN> 1,200g</SPAN></SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 43"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #daeef3; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" rowSpan=4 width=157> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">효과</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=610 colSpan=4> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt"><SPAN> </SPAN>- 척추 골절<SPAN> 40% </SPAN>감소</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 44"> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #b6dde8; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" rowSpan=3> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%; TEXT-INDENT: -12pt; MARGIN: 0cm 0cm 0pt 12pt"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">골밀도 증가 비교</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid"> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt"></SPAN></B> </P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid" width=130> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">요추</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid"> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">히프</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 45"> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid"> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">스테로이드 </SPAN></B></P> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">복용자</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid"> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">3.9%</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid"> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">0.6%</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 46"> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid"> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">스테로이드 </SPAN></B><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">복용 안하는 </SPAN></B></P> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">갱년기 여인</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid"> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">7%</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1.5pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1.5pt solid"> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">3.6%</SPAN></B></P></TD></TR> <TR style="mso-yfti-irow: 47"> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #daeef3; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=157> <P style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 14pt">근거</SPAN></B></P></TD> <TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #f0f0f0; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #f0f0f0; BORDER-RIGHT: black 1pt solid" width=610 colSpan=4> <P style="LINE-HEIGHT: 300%"><B><I><SPAN style="COLOR: black; FONT-SIZE: 12pt">N Engl J Med</SPAN></I></B><B><SPAN style="COLOR: black; FONT-SIZE: 12pt"> 2011; 365:62-70<SPAN style="COLOR: black">July 7, 2011</SPAN></SPAN></B></P> <P style="LINE-HEIGHT: 300%"><B><U><SPAN style="COLOR: black; FONT-SIZE: 12pt">‘Glucocorticoid-Induced Bone Disease’</SPAN></U></B></P> <P style="LINE-HEIGHT: 300%"><B><SPAN style="COLOR: black; FONT-SIZE: 12pt">Robert S. Weinstein, M.D. Division of Endocrinology and Metabolism, the Center for Osteoporosis and Metabolic Bone Diseases, the Department of Internal Medicine, and the Central Arkansas Veterans Healthcare System</SPAN></B></P></TD></TR></TBODY></TABLE></P> 이전글다음글 목록
