뇌졸중 사지 마비를 재활시켜주는 항우울제와 그 처방 내용과 작용 매커니즘 페이지 정보 전성수 0 짧은주소 × 짧은 글주소 복사 Note! 위 주소를 클릭 후, 복사(Ctrl+C)하여 사용하세요. 이전글다음글 목록 본문 <table style="BORDER-BOTTOM: medium none; BORDER-LEFT: medium none; BORDER-COLLAPSE: collapse; BORDER-TOP: medium none; BORDER-RIGHT: medium none" border="1" cellspacing="0" cellpadding="0"> <tbody> <tr> <td width="789" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #92cddc; VERTICAL-ALIGN: middle; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" colspan="2"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><span style="FONT-SIZE: 18pt"><b><br></b></span></p> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%; TEXT-INDENT: 18pt"><span style="FONT-SIZE: 18pt"><b>뇌졸중 사지 마비를 재활시켜주는</b><span style="FONT-SIZE: 18pt"><b> 항우울제와,</b></span></span></p><p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%; TEXT-INDENT: 18pt"><span style="FONT-SIZE: 18pt"><span style="FONT-SIZE: 18pt"></span></span><b><span style="FONT-SIZE: 18pt">그<span><span> </span></span>처방 내용과 작용 매커니즘</span></b></p></td></tr> <tr> <td width="170" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #c6d9f1; VERTICAL-ALIGN: middle; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="FONT-SIZE: 14pt">항 우울제</span></b></p></td> <td width="610" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid"> <p style="LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt"><font size="4">Fluoxetine, Paroxetine 같은<span> SSRI</span>계 항우울제가 단<span> 3</span>개월 복용으로 </font></span></b></p> <p style="LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt"><font size="4">뇌졸중으로 인한<span> </span>사지 마비를 동작시켜 재활케 한다는 놀라운 사실이 </font></span></b></p> <p style="LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt"><font size="4">임상 실험을 통해 입증되었다</font><span>. </span></span></b></p></td></tr> <tr> <td width="170" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #c6d9f1; VERTICAL-ALIGN: middle; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="FONT-SIZE: 14pt">SSRI</span></b></p></td> <td width="610" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid"> <p style="LINE-HEIGHT: 300%"><font size="4"><b><span style="COLOR: black; FONT-SIZE: 12pt">SSRI 계 항우울제는 뇌 내에 신경전달 물질<span> Serotonin </span>을 </span></b><b><span style="COLOR: black; FONT-SIZE: 12pt">증강 시켜주는 약이다 </span></b></font></p> <p style="LINE-HEIGHT: 300%"><strong><span><font size="4">(SSRI=Selective serotonin reuptake inhibitors)</font></span></strong></p></td></tr> <tr> <td width="170" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #c6d9f1; VERTICAL-ALIGN: middle; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><span><strong>Serotonin</strong></span></p></td> <td width="610" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid"> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><font size="4"><b><span style="COLOR: black; FONT-SIZE: 12pt">이<span> Serotonin</span>이라는 물질은 감정을 조절하여 우울증을 치료해주는 물질이지만 </span></b><b><span style="COLOR: black; FONT-SIZE: 12pt">뇌의 운동 신경을 활성화시켜 </span></b><b><span style="COLOR: black; FONT-SIZE: 12pt">사지 동작을 조절한다는 것은 이미 알려져 온 사실이다</span></b></font></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"> </p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="COLOR: black; FONT-SIZE: 12pt"><img width="407" height="366" src="/_dimg/항우울제뇌졸중1.jpg"> </span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><font size="2"><b><span style="FONT-FAMILY: 굴림; COLOR: red">[그림]Serotonin(황색)과 Noradrenalin(녹색)의 작용 분포 </span></b></font><font size="2"><b><span style="FONT-FAMILY: 굴림; COLOR: red">이 두 신경 전달 물질은 </span></b></font></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><font size="2"><b><span style="FONT-FAMILY: 굴림; COLOR: red"> 뇌의 활동을 활발하게 하는 작용을 수행한다.</span></b> </font></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><font size="2"><b><span style="FONT-FAMILY: 굴림; COLOR: red"> Noradrenalin 계 약물로 뇌졸중 사지마비를 치료해보려는 연구도 </span></b></font><font size="2"><b><span style="FONT-FAMILY: 굴림; COLOR: red">있었으나 </span></b></font></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><font size="2"><b><span style="FONT-FAMILY: 굴림; COLOR: red"> Serotonin 처럼 현저한 효과를 보여 주지 못했다.</span></b> </font></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"> </p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="COLOR: black; FONT-SIZE: 12pt">때문에 종종 임상계는<span> SSRI</span>계 항 우울제를 </span></b><b><span style="COLOR: black; FONT-SIZE: 12pt">중풍 환자의 사지마비에 사용해 왔었다<span><span> </span></span></span></b></p></td></tr> <tr> <td width="170" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #c6d9f1; VERTICAL-ALIGN: middle; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="FONT-SIZE: 14pt">항우울제</span></b></p> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="FONT-SIZE: 14pt">Fluoxetine</span></b></p> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="FONT-SIZE: 14pt">투약 시점</span></b></p></td> <td width="610" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid"> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="COLOR: black; FONT-SIZE: 12pt">뇌졸중이 발작하자 마자 </span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 12pt"> </span><b><span style="COLOR: black; FONT-SIZE: 12pt">4-5 시간 내에 혈전 용해제<span> T-PA </span>를 주사하고 </span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 12pt"> </span><b><span style="COLOR: black; FONT-SIZE: 12pt">발작 후<span> 5-10</span>일째로부터 항 우울제를 투약 한다</span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"> </p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="COLOR: black; FONT-SIZE: 12pt">하루 한번<span> 20mg </span>씩<span> 3</span>개월간 투약 </span></b></p></td></tr> <tr style="HEIGHT: 134.4pt; mso-yfti-irow: 5"> <td width="170" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #c6d9f1; HEIGHT: 134.4pt; VERTICAL-ALIGN: middle; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="FONT-SIZE: 14pt">90</span></b><b><span style="FONT-SIZE: 14pt">일째</span></b></p> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="FONT-SIZE: 14pt">효과 평가</span></b></p></td> <td width="610" style="BORDER-BOTTOM: black 1pt solid; TEXT-ALIGN: center; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; HEIGHT: 134.4pt; VERTICAL-ALIGN: middle; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid"> <table style="BORDER-BOTTOM: medium none; TEXT-ALIGN: center; BORDER-LEFT: medium none; BORDER-COLLAPSE: collapse; BORDER-TOP: medium none; BORDER-RIGHT: medium none" border="1" cellspacing="0" cellpadding="0"> <tbody> <tr> <td width="470" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 352.35pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #b6dde8; VERTICAL-ALIGN: middle; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" colspan="6"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 12pt">90일 째 사지 동작 점수</span></b></p></td></tr> <tr> <td width="117" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 87.85pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"> </p></td> <td width="118" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 88.6pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" colspan="2"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">Fluoxetine군</span></b></p></td> <td width="117" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 87.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" colspan="2"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">위약군</span></b></p></td> <td width="117" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 88pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">동작가능한</span></b></p> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">최고 점수</span></b></p></td></tr> <tr> <td width="117" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 87.85pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">상부 사지</span></b></p></td> <td width="118" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 88.6pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" colspan="2"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">29.7</span></b></p></td> <td width="117" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 87.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" colspan="2"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">16.2</span></b></p></td> <td width="117" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 88pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">66</span></b></p></td></tr> <tr> <td width="117" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 87.85pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">하부 사지</span></b></p></td> <td width="118" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 88.6pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" colspan="2"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">24</span></b></p></td> <td width="117" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 87.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" colspan="2"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">18.9</span></b></p></td> <td width="117" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 88pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">34</span></b></p></td></tr> <tr> <td width="470" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 352.35pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fabf8f; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" colspan="6"> <p style="LINE-HEIGHT: 300%"><b><span style="FONT-FAMILY: 굴림; COLOR: #404040; FONT-SIZE: 12pt">FMMS(Fugl-Meyer motor scale) </span></b><b><span style="COLOR: #404040; FONT-SIZE: 12pt">균형</span></b> <b><span style="COLOR: #404040; FONT-SIZE: 12pt">감각</span></b> <b><span style="COLOR: #404040; FONT-SIZE: 12pt">관절</span></b> <b><span style="COLOR: #404040; FONT-SIZE: 12pt">동작</span></b> </p> <p style="LINE-HEIGHT: 300%"><b><span style="COLOR: #404040; FONT-SIZE: 12pt">채점방식을</span></b> <b><span style="COLOR: #404040; FONT-SIZE: 12pt">적용</span></b></p></td></tr> <tr style="HEIGHT: 8.1pt; mso-yfti-irow: 5"> <td width="470" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 352.35pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; HEIGHT: 8.1pt; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: #ffffff" colspan="6"> <p style="LINE-HEIGHT: 300%"> </p></td></tr> <tr> <td width="470" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 352.35pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #b6dde8; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" colspan="6"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 12pt">90일 째 대인 관계 활성도</span></b></p></td></tr> <tr> <td width="144" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 107.75pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" colspan="2"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"> </p></td> <td width="151" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 4cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" colspan="2"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">Fluoxetine군</span></b></p></td> <td width="175" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 131.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" colspan="2"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">위약군</span></b></p></td></tr> <tr> <td width="144" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 107.75pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" colspan="2"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">활성화된 자</span></b></p></td> <td width="151" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 4cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" colspan="2"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">26%</span></b></p></td> <td width="175" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 131.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" colspan="2"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">5%</span></b></p></td></tr> <tr> <td width="470" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 352.35pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fabf8f; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid" colspan="6"> <p style="LINE-HEIGHT: 300%; TEXT-INDENT: 6pt; mso-char-indent-count: .5"><b><span style="COLOR: black; FONT-SIZE: 12pt">MRS: modified Rankin<span> </span>채점 방식</span></b></p></td></tr> <tr height="0"> <td width="117" style="BORDER-BOTTOM: #ffffff; BORDER-LEFT: #ffffff; BACKGROUND-COLOR: transparent; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: #ffffff"></td> <td width="27" style="BORDER-BOTTOM: #ffffff; BORDER-LEFT: #ffffff; BACKGROUND-COLOR: transparent; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: #ffffff"></td> <td width="92" style="BORDER-BOTTOM: #ffffff; BORDER-LEFT: #ffffff; BACKGROUND-COLOR: transparent; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: #ffffff"></td> <td width="60" style="BORDER-BOTTOM: #ffffff; BORDER-LEFT: #ffffff; BACKGROUND-COLOR: transparent; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: #ffffff"></td> <td width="58" style="BORDER-BOTTOM: #ffffff; BORDER-LEFT: #ffffff; BACKGROUND-COLOR: transparent; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: #ffffff"></td> <td width="117" style="BORDER-BOTTOM: #ffffff; BORDER-LEFT: #ffffff; BACKGROUND-COLOR: transparent; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: #ffffff"></td></tr></tbody></table> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"> </p> <table style="BORDER-BOTTOM: medium none; BORDER-LEFT: medium none; BORDER-COLLAPSE: collapse; BORDER-TOP: medium none; BORDER-RIGHT: medium none" border="1" cellspacing="0" cellpadding="0"> <tbody> <tr> <td width="470" style="BORDER-BOTTOM: black 1pt solid; TEXT-ALIGN: center; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 352.35pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #b6dde8; VERTICAL-ALIGN: middle; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid" colspan="3"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 12pt">90일 간 부작용</span></b></p></td></tr> <tr> <td width="138" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 103.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"> </p></td> <td width="157" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 117.45pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">Fluoxetine군</span></b></p></td> <td width="175" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 131.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">위약군</span></b></p></td></tr> <tr> <td width="138" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 103.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">저혈증</span></b></p></td> <td width="157" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 117.45pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">4%</span></b></p></td> <td width="175" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 131.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">4%</span></b></p></td></tr> <tr> <td width="138" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 103.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">구역</span></b></p></td> <td width="157" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 117.45pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">9%</span></b></p></td> <td width="175" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 131.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">0</span></b></p></td></tr> <tr> <td width="138" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 103.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">설사</span></b></p></td> <td width="157" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 117.45pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">12%</span></b></p></td> <td width="175" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 131.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">7%</span></b></p></td></tr> <tr> <td width="138" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 103.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">복통</span></b></p></td> <td width="157" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 117.45pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">4%</span></b></p></td> <td width="175" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 131.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">4%</span></b></p></td></tr> <tr> <td width="138" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 103.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">간효소 수치</span></b></p></td> <td width="157" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 117.45pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">9%</span></b></p></td> <td width="175" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 131.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">18%</span></b></p></td></tr> <tr> <td width="138" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 103.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">정신 이상 증상</span></b></p></td> <td width="157" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 117.45pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">5%</span></b></p></td> <td width="175" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 131.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">7%</span></b></p></td></tr> <tr> <td width="138" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 103.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">불면증</span></b></p></td> <td width="157" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 117.45pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">33%</span></b></p></td> <td width="175" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 131.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">36%</span></b></p></td></tr> <tr> <td width="138" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 103.7pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #d6e3bc; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">부분 경련</span></b></p></td> <td width="157" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 117.45pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">2%</span></b></p></td> <td width="175" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ffffff; PADDING-LEFT: 5.4pt; WIDTH: 131.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #e5b8b7; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">0</span></b></p></td></tr></tbody></table></td></tr> <tr> <td width="789" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #99ffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid" colspan="2"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 15pt">작용</span></b><b><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 15pt"> </span></b><b><span style="COLOR: black; FONT-SIZE: 15pt">매커니즘</span></b></p></td></tr> <tr> <td width="170" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #c6d9f1; VERTICAL-ALIGN: middle; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="FONT-SIZE: 14pt">뇌의 일차</span></b></p> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="FONT-SIZE: 14pt">운동</span></b></p> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="FONT-SIZE: 14pt">피질에 작용</span></b></p></td> <td width="610" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid"> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="COLOR: black; FONT-SIZE: 12pt">뇌의 일차<span> </span>운동<span> </span>피질<span>(Primary motor cortex)</span>에는 </span></b><b><span style="COLOR: black; FONT-SIZE: 12pt">운동을 지배하는 영역이 있다.</span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="COLOR: black; FONT-SIZE: 12pt">이를</span></b><b><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 12pt"> Serotonin 이 활성화 시켜주고 있다.</span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 12pt"><span></span></span></b><b><span style="COLOR: black; FONT-SIZE: 12pt">뇌졸중으로 사지마비가 된 자는 </span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="COLOR: black; FONT-SIZE: 12pt">바로 이 영역의 신경이 활동을 하지 못하고 있는 것이다.</span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 12pt"></span></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="COLOR: black; FONT-SIZE: 12pt"><img src="/_dimg/항우울제뇌졸중2.jpg"> </span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"> </p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="COLOR: black; FONT-SIZE: 12pt"><img src="/_dimg/항우울제뇌졸중3.jpg"></span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><font size="2"><b><span style="FONT-FAMILY: 굴림; COLOR: red">[그림] 뇌의 일차 운동 신경 영역 각 동작을 지배하는 위치</span></b></font></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 14pt"></span></b> </p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 14pt">Fluoxetine, </span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 14pt">Paroxetine, </span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 12pt">Citalopram 같은</span></b><b><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 12pt"> SSRI 제제는</span></b> </p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="COLOR: black; FONT-SIZE: 12pt">뇌의 일차<span> </span>운동<span> </span>피질 동박 영역에 </span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 12pt">Serotonin을 증강 시켜주기 때문에</span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="COLOR: black; FONT-SIZE: 12pt">사지마비를 재활시킬 수가 있다 </span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="COLOR: black; FONT-SIZE: 12pt">(Curr Opin Neurobiol 1997:7:820-825)</span></b></p></td></tr> <tr> <td width="170" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #c6d9f1; VERTICAL-ALIGN: middle; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="FONT-SIZE: 14pt">해마에 작용</span></b></p></td> <td width="610" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid"> <p style="LINE-HEIGHT: 300%; TEXT-INDENT: 6pt; BACKGROUND: #ffffcc; mso-char-indent-count: .5"><b><span style="COLOR: black; FONT-SIZE: 12pt">또한 사지마비 환자는 </span></b><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 12pt"> </span><b><span style="COLOR: black; FONT-SIZE: 12pt">동작을 계획하고 결정하는 </span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 12pt"> </span><b><span style="COLOR: black; FONT-SIZE: 12pt">해마</span></b><b><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 12pt">(Hippocampal)영역이 활동을 못하고 있다.</span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 12pt"> <img width="369" height="286" src="/_dimg/항우울제뇌졸중4.jpg"></span></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><span style="FONT-FAMILY: 굴림; COLOR: black"><font size="2"></font></span> </p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><font size="2"><b><span style="FONT-FAMILY: 굴림; COLOR: red">[그림]해마(Hippocampus)는 기억과 감정을 주관하는 곳이며</span></b><span style="FONT-FAMILY: 굴림; COLOR: black"></span></font></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><font size="2"><b><span style="FONT-FAMILY: 굴림; COLOR: red"> 일상적인 동작 중 습관적 동작을 기억하고 계획하고 조절하는바</span></b><span style="FONT-FAMILY: 굴림; COLOR: black"></span></font></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><font size="2"><span style="FONT-FAMILY: 굴림; COLOR: black"> </span><b><span style="FONT-FAMILY: 굴림; COLOR: red"> Serotonin 이 이러한 조절을 활성화 시킨다</span></b></font></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="COLOR: black; FONT-SIZE: 12pt"></span></b> </p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="COLOR: black; FONT-SIZE: 12pt">바로 이 곳에서도</span></b><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 12pt"> </span><b><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 12pt">Serotonin 이 신경 전달 물질로 대량 사용되는 곳이다</span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="COLOR: black; FONT-SIZE: 12pt">(Journal of Neuroscience Research 2009:87; 112-`122)</span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b></b> </p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 12pt">SSRI 항우울제는 해마에서 serotonin 을 증강시켜</span></b><b></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="COLOR: black; FONT-SIZE: 12pt">사지마비를 개선한다</span></b></p></td></tr> <tr> <td width="170" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #c6d9f1; VERTICAL-ALIGN: middle; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="FONT-SIZE: 14pt">항염작용통한</span></b></p> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="FONT-SIZE: 14pt">신경 보호</span></b></p></td> <td width="610" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid"> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="FONT-FAMILY: 굴림; COLOR: black; FONT-SIZE: 12pt">SSRI 제제는 항염 작용을 발휘하는 물질이며</span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="BACKGROUND: #ffffcc; COLOR: black; FONT-SIZE: 12pt">뇌의 신경을 보호한다고 발표자들은 설명했다.</span></b></p></td></tr> <tr> <td width="170" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #c6d9f1; VERTICAL-ALIGN: middle; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid"> <p style="TEXT-ALIGN: center; LINE-HEIGHT: 300%"><b><span style="FONT-SIZE: 14pt">근거</span></b></p></td> <td width="610" style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffffcc; VERTICAL-ALIGN: middle; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid"> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="COLOR: black; FONT-SIZE: 12pt">본 임상은 프랑스<span> Tulouse </span>의대 연구팀이</span></b></p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="COLOR: black; FONT-SIZE: 12pt">허혈성 뇌졸중으로 인한 사지 사지 마비 환자를 대상으로 하여 임상 시험한 결과이며 영국 의학지<span> Lancet</span>를 통해 발표한 </span></b><b><span style="COLOR: black; FONT-SIZE: 12pt">내용이다<span>. </span></span></b></p> <p style="LINE-HEIGHT: 300%"><b><span style="COLOR: black; FONT-SIZE: 12pt">The Lancet Neurology, Early Online Publication, 10 January 2011 doi:10.1016/S1474-4422(10)70314-8</span></b><span><a href="http://www.thelancet.com/popup?fileName=cite-using-doi" target="newWin"> </a></span><table width="100%" cellspacing="0" cellpadding="0"> <tbody> <tr> <td style="BORDER-BOTTOM: #ffffff; BORDER-LEFT: #ffffff; BACKGROUND-COLOR: transparent; VERTICAL-ALIGN: middle; BORDER-TOP: #ffffff; BORDER-RIGHT: #ffffff"> <div> <p><span><font size="2"></font></span> </p></div></td></tr></tbody></table><a href="http://www.thelancet.com/popup?fileName=cite-using-doi" target="newWin"><b><span style="COLOR: windowtext; FONT-SIZE: 12pt; TEXT-DECORATION: none; text-underline: none">Cite or Link Using DOI</span></b></a> <b><span style="COLOR: black; FONT-SIZE: 12pt">Fluoxetine for motor recovery after acute ischaemic stroke (FLAME): a randomised placebo-controlled trial Neurology Department, Centre Hospitalier Universitaire de Toulouse, Hopital Purpan, Toulouse, France</span></b><p> </p> <p style="LINE-HEIGHT: 300%; BACKGROUND: #ffffcc"><b><span style="COLOR: black; FONT-SIZE: 12pt">Neurology Department, Centre Hospitalier Universitaire de Toulouse, Hopital Purpan, Toulouse, France Neurology Department, Centre Hospitalier Universitaire de Toulouse, Hopital Purpan, Toulouse, France</span></b></p></td></tr></tbody></table> 이전글다음글 목록
