당뇨 병 자가 아스피린을 복용 할 때는 12 시간에 한번씩 1일 2회 복용 해야 한다 페이지 정보 전성수 0 짧은주소 × 짧은 글주소 복사 Note! 위 주소를 클릭 후, 복사(Ctrl+C)하여 사용하세요. 이전글다음글 목록 본문 <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: red; FONT-SIZE: 20pt"><strong>당뇨 병 자가 아스피린을 복용 할 때는 </strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: red; FONT-SIZE: 20pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: red; FONT-SIZE: 20pt">12 </span><span style="COLOR: red; FONT-SIZE: 20pt">시간에 한번 씩<span> 1</span>일<span> 2</span>회 복용 해야 한다</span></strong></p><p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: red; FONT-SIZE: 20pt"><br></span></strong></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><span><strong></strong></span></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="FONT-SIZE: 14pt">2</span><span style="FONT-SIZE: 14pt">형 당뇨병 자가<span><span> </span></span>합병증 재발을 방지 하기 위하여</span></strong></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong></strong> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>아스피린을<span> 1</span>일<span> 1</span>회 복용 하고 있는 자들이 많다</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>그러나 무려<span> 42%</span>나 되는 자들이 아스피린<span> 1</span>일 <span>1</span>회 요법으로 인해</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>내성을 일으키고 있음이 밝혀졌다</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>또한<span><span> </span>1</span>일<span> 1</span>회 요법에서 아스피린 내성인자들이 </strong></span><strong><span style="FONT-SIZE: 14pt">1</span><span style="FONT-SIZE: 14pt">일<span> 2</span>회 요법을 실시 할 때는 </span></strong></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong></strong> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>내성 자중<span> 62%</span>기 아스피린 효과를 나태내었다</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>이는 파리 디드로 의대 연구 팀의 연구 결과이며</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="FONT-SIZE: 14pt"> </span><span style="FONT-SIZE: 14pt">미국 심장 학회 학술지<span>(Heart) </span>최신호를 통해 </span></strong><span style="FONT-SIZE: 14pt"><strong>그 이유 와 함께 발표된 내용이다</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span><strong></strong></span> </p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span><strong></strong></span> </p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span><strong><img width="615" height="323" style="WIDTH: 614px; HEIGHT: 428px" src="/_dimg/1%20혈소판.bmp"></strong></span></p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span><strong></strong></span> </p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: black; FONT-SIZE: 14pt"><!--?xml:namespace prefix = v ns = "urn:schemas-microsoft-com:vml" /--><v:shapetype id="_x0000_t75" o:spt="75" stroked="f" filled="f" path="m@4@5l@4@11@9@11@9@5xe" o:preferrelative="t" coordsize="21600,21600"><v:stroke joinstyle="miter"></v:stroke><v:formulas><v:f eqn="if lineDrawn pixelLineWidth 0"></v:f><v:f eqn="sum @0 1 0"></v:f><v:f eqn="sum 0 0 @1"></v:f><v:f eqn="prod @2 1 2"></v:f><v:f eqn="prod @3 21600 pixelWidth"></v:f><v:f eqn="prod @3 21600 pixelHeight"></v:f><v:f eqn="sum @0 0 1"></v:f><v:f eqn="prod @6 1 2"></v:f><v:f eqn="prod @7 21600 pixelWidth"></v:f><v:f eqn="sum @8 21600 0"></v:f><v:f eqn="prod @7 21600 pixelHeight"></v:f><v:f eqn="sum @10 21600 0"></v:f></v:formulas><v:path o:connecttype="rect" gradientshapeok="t" o:extrusionok="f"></v:path><!--?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" /--><o:lock aspectratio="t" v:ext="edit"></o:lock></v:shapetype></span></p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">1[</span><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">그림<span>] </span>생명의 피<span> 3 </span>총사<span> : White bood cell(</span>백혈구<span>) </span>혈소판<span>(Platelet) </span></span></strong></p> <p align="left" style="LINE-HEIGHT: normal; TEXT-INDENT: -42pt; MARGIN: 0cm 0cm 0pt 42pt"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"> </span><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">적혈구<span>(Red blood cell) </span>혈소판은 수시로 파열되는 미세 혈관 벽을 막아 출혈을 방지해 주는 중요한 역활을 하지만 혈관을 아주 막아 버려 만가지 병을 유발하는 원인이 된다</span></strong></p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span><strong></strong></span> </p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: black; FONT-SIZE: 14pt"></span></p> <p align="left" style="LINE-HEIGHT: normal; TEXT-INDENT: -56pt; MARGIN: 0cm 0cm 0pt 56pt; mso-char-indent-count: -4.0"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"></span></strong> </p> <p align="left" style="LINE-HEIGHT: normal; TEXT-INDENT: -56pt; MARGIN: 0cm 0cm 0pt 56pt; mso-char-indent-count: -4.0"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"></span></strong> </p> <p align="left" style="LINE-HEIGHT: normal; TEXT-INDENT: -56pt; MARGIN: 0cm 0cm 0pt 56pt; mso-char-indent-count: -4.0"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"><img width="611" height="548" src="/_dimg/2%20ms.bmp"></span></strong></p> <p align="left" style="LINE-HEIGHT: normal; TEXT-INDENT: -56pt; MARGIN: 0cm 0cm 0pt 56pt; mso-char-indent-count: -4.0"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">[</span><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">그림<span>] </span>죽상 동맥경화가 있는 심장 질환 자 담배 피우는 자 당뇨병자 들은 매 순간 생성되는 혈소판 생성 량이 많아서 아스피린 하루 한번 복용만으로는 혈전 예방을 하기 어렵다</span></strong></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p align="left" style="LINE-HEIGHT: normal; TEXT-INDENT: -42pt; MARGIN: 0cm 0cm 0pt 42pt"><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"><strong></strong></span> </p> <p align="left" style="LINE-HEIGHT: normal; TEXT-INDENT: -42pt; MARGIN: 0cm 0cm 0pt 42pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong><img width="627" height="255" style="WIDTH: 626px; HEIGHT: 433px" src="/_dimg/fig-1x.png">Fig-1x</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: #3333ff; FONT-SIZE: 20pt"></span></strong> </p><span style="COLOR: #3333ff; FONT-SIZE: 20pt"> <p style="TEXT-INDENT: -35pt; MARGIN: 0cm 0cm 0pt 40pt; mso-char-indent-count: -2.5; mso-para-margin-left: .5gd"><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림">[</font></span><strong><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-ascii-font-family: 굴림; mso-hansi-font-family: 굴림">그림</span><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림">] OPD: </font></span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold; mso-bidi-font-size: 12.0pt">아스피린<span> 1</span>일<span> 1</span>회 목용자들ㅏ타나있다</span></strong></p> <p style="TEXT-INDENT: 28pt; MARGIN: 0cm 0cm 0pt 30pt; mso-para-margin-left: 3.0gd"><strong><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold; mso-bidi-font-size: 12.0pt">BID : </span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold; mso-bidi-font-size: 12.0pt">아스피린<span> 1</span>일<span> 2</span>회 복용자 </span></strong></p> <p style="TEXT-INDENT: 28pt; MARGIN: 0cm 0cm 0pt 30pt; mso-para-margin-left: 3.0gd"><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold; mso-bidi-font-size: 12.0pt"><strong>세로<span>: </span>혈소판 음집 력<span> 20% </span>이상이면 아스피린 내성</strong></span></p> <p style="TEXT-INDENT: 56pt; MARGIN: 0cm 0cm 0pt; mso-char-indent-count: 4.0"><strong><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold; mso-bidi-font-size: 12.0pt">OPD) </span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold; mso-bidi-font-size: 12.0pt">의<span> 42%</span>기 아스피린 내성임이 밝혀졌다</span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 10pt"></span></strong></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong></strong> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: #3333ff; FONT-SIZE: 20pt">1</span><span style="COLOR: #3333ff; FONT-SIZE: 20pt">일<span> 1</span>회<span>. </span>요법은 <span>42%</span>가 아스피린 효과를 상실<span><span> </span></span></span></strong></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>본 임상은 <span>2</span>형 당뇨병 자 중에서 </strong></span><span style="FONT-SIZE: 14pt"><strong>아스피린을 복용해야만 하는 합병증을 지닌 자</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="FONT-SIZE: 14pt"> 92</span><span style="FONT-SIZE: 14pt">명<span>(</span>평균 <span>64</span>세<span>)</span>을 대상으로 하여 두 군으로 나누어</span></strong></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong></strong> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>무작위 교차 비교 임상을 실시했다 </strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="FONT-SIZE: 14pt">A</span><span style="FONT-SIZE: 14pt">군은<span> 1</span>일<span> 1</span>회<span> 150mg </span>을 오전<span> 7-9</span>시에 <span>14</span>일간 복용토록 했으며</span></strong></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong></strong> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="FONT-SIZE: 14pt">B,</span><span style="FONT-SIZE: 14pt">근은<span> 1</span>일<span> 2</span>회 <span>1</span>회<span> 75mg</span>을 오전 과 오후<span> 7-9</span>시에 <span>14</span>일간</span></strong></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong></strong> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>복용토록 했으며 무작위 추출<span><span> </span></span>교차 비교 임상을 실시한 내용이다</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong> </strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>그 결과 아래 표에서 처럼</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>아스피린<span> 1</span>일<span> 1</span>회 목용자들의<span> 42%</span>기 아스피린 내성임이 밝혀졌다</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <table style="BORDER-BOTTOM: medium none; BORDER-LEFT: medium none; BORDER-COLLAPSE: collapse; BORDER-TOP: medium none; BORDER-RIGHT: medium none; mso-yfti-tbllook: 1184; mso-padding-alt: 0cm 5.4pt 0cm 5.4pt" border="1" cellspacing="0" cellpadding="0"> <tbody> <tr style="mso-yfti-irow: 0; mso-yfti-firstrow: yes"> <td width="225" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: windowtext 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 168.45pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: windowtext 1pt solid; BORDER-RIGHT: windowtext 1pt solid"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p></td> <td width="390" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 292.75pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: windowtext 1pt solid; BORDER-RIGHT: windowtext 1pt solid" colspan="2"> <p align="center" style="TEXT-ALIGN: center; LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>아스피린 복용 자<span> 92</span>명 </strong></span></p></td></tr> <tr> <td width="225" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: windowtext 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 168.45pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffc000; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p></td> <td width="185" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 139pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffc000; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="FONT-SIZE: 14pt">1</span><span style="FONT-SIZE: 14pt">일<span> 1</span>회 복용 군 </span></strong></p></td> <td width="205" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 153.75pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffc000; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="FONT-SIZE: 14pt">1</span><span style="FONT-SIZE: 14pt">일<span> 2</span>회 복용 군 </span></strong></p></td></tr> <tr> <td width="225" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: windowtext 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 168.45pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p></td> <td width="185" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 139pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>아침<span> 7</span>시<span>-9</span>시 </strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="FONT-SIZE: 14pt">1</span><span style="FONT-SIZE: 14pt">회<span> 150mg </span></span></strong></p></td> <td width="205" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 153.75pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>아침<span> 7-9</span>시<span> 75mg </span></strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>저녁<span> 7-9</span>시<span> 75mg </span></strong></span></p></td></tr> <tr> <td width="225" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: windowtext 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 168.45pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>혈소판 응집도<span>(MAI)</span>가</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="FONT-SIZE: 14pt">20%</span><span style="FONT-SIZE: 14pt">를 초과 하는 자</span></strong></p></td> <td width="185" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 139pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #99ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p align="center" style="TEXT-ALIGN: center; LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>42%</strong></span></p></td> <td width="205" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 153.75pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #99ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p align="center" style="TEXT-ALIGN: center; LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>17%</strong></span></p></td></tr> <tr> <td width="615" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: windowtext 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 461.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ddd9c3; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid; mso-background-themecolor: background2; mso-background-themeshade: 230" colspan="3"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>대상자<span>:<span> </span>2</span>형 당뇨병 자 로서 관상동맥 질환 지니자</strong></span></p> <p align="left" style="LINE-HEIGHT: normal; TEXT-INDENT: 40pt; MARGIN: 0cm 0cm 0pt; mso-char-indent-count: 4.0"><strong><span style="FONT-SIZE: 14pt; mso-bidi-font-family: AdvTTd310d995">염증 지수<span>(hsCRP </span>높은지 혈소판 수 높은지 끽연 자</span></strong></p></td></tr> <tr style="mso-yfti-irow: 5; mso-yfti-lastrow: yes"> <td width="615" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: windowtext 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 461.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffccff; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid" colspan="3"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="FONT-SIZE: 14pt">Apsirin</span><span style="FONT-SIZE: 14pt">은 장용정이 아닌 <span>Aspriin lysinate </span>분말을 사용</span></strong></p></td></tr></tbody></table> <p style="MARGIN: 0cm 0cm 10pt"><span><strong></strong></span> </p> <p style="MARGIN: 0cm 0cm 10pt"><span><strong></strong></span> </p> <p style="MARGIN: 0cm 0cm 10pt"><span style="LINE-HEIGHT: 115%; COLOR: black; FONT-SIZE: 14pt"> </span></p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"></span></strong> </p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"><img src="/_dimg/3%20뇌졸중.bmp"></span></strong></p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">[</span><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">그림<span>] </span>뇌졸중과 심장 마비를 일으킬 위험이 큰 자들은</span></strong></p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"> </span><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">아스피린을 복용하되 아스피린이 하루<span> 24</span>시간 계속 작용할 수</span></strong></p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"> </span><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">있게 해주어야 한다</span></strong></p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"> </span><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">아스피린 소량을 하루 한번 이상 수회 복용해야 한다</span></strong></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong><img width="567" height="284" style="WIDTH: 566px; HEIGHT: 389px" src="/_dimg/fig-2x.png"> </strong></span></p><span style="COLOR: #3333ff; FONT-SIZE: 20pt"> <p style="MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림">[</font></span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-ascii-font-family: 굴림; mso-hansi-font-family: 굴림">그림</span><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림">] <span> </span></font></span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold; mso-bidi-font-size: 12.0pt"> 1</span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold; mso-bidi-font-size: 12.0pt">일<span> 1</span>회 요법으로 아스피린의 내성을 나타낸 자들이</span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 10pt"></span></strong></p> <p align="left" style="LINE-HEIGHT: normal; TEXT-INDENT: -10pt; MARGIN: 0cm 0cm 0pt 80pt; mso-para-margin-left: 7.0gd"><strong><span style="COLOR: red"><font size="2"> </font></span><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">1</span><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">일<span> 2</span>회 요법을 실시할 때는 아래 표에서 처럼<span> 62%</span>가 아스피린 효과를 나타내었다</span><span style="COLOR: red"><font size="2"> </font></span></strong></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong></strong> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong>아스피린 내성 자가 <span>1</span>일 <span>2</span>회<span>. </span>요법을 실시하면</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: #3333ff; FONT-SIZE: 20pt">62%</span><span style="COLOR: #3333ff; FONT-SIZE: 20pt">가 아스피린 효과를 나타낸다</span></strong></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><span><strong></strong></span></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>본 임상은 <span>1</span>일<span> 1</span>회 요법으로 아스피린의 내성을 나타낸 자들이</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="FONT-SIZE: 14pt">1</span><span style="FONT-SIZE: 14pt">일<span> 2</span>회 요법을 실시할 때는 </span></strong><span style="FONT-SIZE: 14pt"><strong>아래 표에서 처럼 <span>62%</span>가 아스피린 효과를 나타내었다</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="MARGIN: 0cm 0cm 10pt"><span><strong></strong></span> </p> <table style="BORDER-BOTTOM: medium none; BORDER-LEFT: medium none; BORDER-COLLAPSE: collapse; BORDER-TOP: medium none; BORDER-RIGHT: medium none; mso-yfti-tbllook: 1184; mso-padding-alt: 0cm 5.4pt 0cm 5.4pt" border="1" cellspacing="0" cellpadding="0"> <tbody> <tr style="mso-yfti-irow: 0; mso-yfti-firstrow: yes"> <td width="615" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: windowtext 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 461.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: windowtext 1pt solid; BORDER-RIGHT: windowtext 1pt solid" colspan="3"> <p align="center" style="TEXT-ALIGN: center; LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>아스피린<span> 1</span>일<span> 1</span>회 복용으로 내성 인자</strong></span></p> <p align="center" style="TEXT-ALIGN: center; LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p></td></tr> <tr> <td width="272" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: windowtext 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 203.85pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffc000; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p></td> <td width="16" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 11.8pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffc000; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p align="center" style="TEXT-ALIGN: center; LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p></td> <td width="327" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 245.55pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffc000; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p align="center" style="TEXT-ALIGN: center; LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="FONT-SIZE: 14pt">1</span><span style="FONT-SIZE: 14pt">일<span> 2</span>회 복용할 때</span></strong></p></td></tr> <tr> <td width="272" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: windowtext 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 203.85pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p></td> <td width="16" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 11.8pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p align="center" style="TEXT-ALIGN: center; LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p></td> <td width="327" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 245.55pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p align="center" style="TEXT-ALIGN: center; LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>아침<span> 7-9</span>시<span> 75mg</span></strong></span></p> <p align="center" style="TEXT-ALIGN: center; LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>저녁<span> 7-9</span>시<span> 75mg</span></strong></span></p></td></tr> <tr> <td width="272" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: windowtext 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 203.85pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>아스피린 효과를 나타낸 자 </strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p></td> <td width="16" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 11.8pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #99ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p align="center" style="TEXT-ALIGN: center; LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p></td> <td width="327" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 245.55pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #99ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p align="center" style="TEXT-ALIGN: center; LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>62%</strong></span></p></td></tr> <tr> <td width="615" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: windowtext 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 461.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ddd9c3; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid; mso-background-themecolor: background2; mso-background-themeshade: 230" colspan="3"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>대상자<span>:<span> </span>2</span>형 당뇨병 자로서 관상 동맥 질환 지니자</strong></span></p> <p align="left" style="LINE-HEIGHT: normal; TEXT-INDENT: 40pt; MARGIN: 0cm 0cm 0pt; mso-char-indent-count: 4.0"><span style="FONT-SIZE: 14pt; mso-bidi-font-family: AdvTTd310d995"><strong>염증 지수<span>(hsCRP </span>높은지 혈소판 수 높은지 끽연 자</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p></td></tr> <tr style="mso-yfti-irow: 5; mso-yfti-lastrow: yes"> <td width="615" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: windowtext 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 461.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffccff; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid" colspan="3"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="FONT-SIZE: 14pt">Apsirin</span><span style="FONT-SIZE: 14pt">은 장용정이 아닌<span> Aspriin lysinate </span>분말을 사용</span></strong></p></td></tr></tbody></table> <p style="MARGIN: 0cm 0cm 10pt"><span><strong></strong></span> </p> <p style="MARGIN: 0cm 0cm 10pt"><span><strong></strong></span> </p> <p style="MARGIN: 0cm 0cm 10pt"><span><strong></strong></span> </p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span><strong></strong></span> </p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: red; FONT-SIZE: 14pt"></span></p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"></span></strong> </p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"></span></strong> </p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"><img width="703" height="334" style="WIDTH: 702px; HEIGHT: 394px" src="/_dimg/4%20platel;t.bmp"></span></strong></p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">[</span><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">그림<span>] </span>아스피린을 하루 한번만 복용하면 복용했을 즉시는</span></strong></p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"> </span><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">모든 혈소판이 불활성화 되지만 두 시간만 지나면</span></strong><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"> </span><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">새로운 혈소판이 생겨난다</span></strong></p> <p style="MARGIN: 0cm 0cm 10pt"><span><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong>아스피린은 복용 후 <span>2</span>시간 째 부터 </strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong>아스피린 내성 율 시간 따라 증가 </strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong></strong></span> </p> <p style="MARGIN: 0cm 0cm 10pt"><span><strong></strong></span> </p> <p style="MARGIN: 0cm 0cm 10pt"><span style="LINE-HEIGHT: 115%; FONT-SIZE: 14pt"><strong>아스피린을<span> 1</span>일<span> 1</span>회만 복용하는 경우는 </strong></span></p> <p style="MARGIN: 0cm 0cm 10pt"><span style="LINE-HEIGHT: 115%; FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="MARGIN: 0cm 0cm 10pt"><span style="LINE-HEIGHT: 115%; FONT-SIZE: 14pt"><strong>복용 후 <span>2</span>시간이면 아스피린 내성 혈소판이<span> 4% </span>증가하며 </strong></span></p> <p style="MARGIN: 0cm 0cm 10pt"><span style="LINE-HEIGHT: 115%; FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="MARGIN: 0cm 0cm 10pt"><strong><span style="LINE-HEIGHT: 115%; FONT-SIZE: 14pt">24</span><span style="LINE-HEIGHT: 115%; FONT-SIZE: 14pt">시간 째는 무려<span> 28%</span>가 아스피린이 결합되지 않은 </span></strong><span style="LINE-HEIGHT: 115%; FONT-SIZE: 14pt"><strong>새로운 혈소판이 생겨난다 <br></strong></span></p> <p style="MARGIN: 0cm 0cm 10pt"><span><span><strong></strong></span></span> </p> <table style="BORDER-BOTTOM: medium none; BORDER-LEFT: medium none; BORDER-COLLAPSE: collapse; BORDER-TOP: medium none; BORDER-RIGHT: medium none; mso-yfti-tbllook: 1184; mso-padding-alt: 0cm 5.4pt 0cm 5.4pt" border="1" cellspacing="0" cellpadding="0"> <tbody> <tr style="mso-yfti-irow: 0; mso-yfti-firstrow: yes"> <td width="615" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: windowtext 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 461.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: windowtext 1pt solid; BORDER-RIGHT: windowtext 1pt solid" colspan="3"> <p align="center" style="TEXT-ALIGN: center; LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>아스피린<span> 1</span>일<span> 1</span>회 복용 시 내성 화 율 시간 마다 증가 </strong></span></p> <p align="center" style="TEXT-ALIGN: center; LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p></td></tr> <tr> <td width="272" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: windowtext 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 203.85pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffc000; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p></td> <td width="16" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 11.8pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffc000; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p align="center" style="TEXT-ALIGN: center; LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p></td> <td width="327" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 245.55pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffc000; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p align="center" style="TEXT-ALIGN: center; LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="FONT-SIZE: 14pt">1</span><span style="FONT-SIZE: 14pt">일<span> 1</span>회 복용할 때</span></strong></p></td></tr> <tr> <td width="272" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: windowtext 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 203.85pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p></td> <td width="16" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 11.8pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p align="center" style="TEXT-ALIGN: center; LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p></td> <td width="327" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 245.55pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p align="center" style="TEXT-ALIGN: center; LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>아침<span> 7-9</span>시 <span>150mg</span></strong></span></p></td></tr> <tr> <td width="272" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: windowtext 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 203.85pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>아스피린 효과 상실 자</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>시간마다 중가 </strong></span></p></td> <td width="16" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 11.8pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #99ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p align="center" style="TEXT-ALIGN: center; LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p></td> <td width="327" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 245.55pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #99ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>복용 후<span> 2</span>시간 째<span>-----4%</span></strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>복용 후<span> 24</span>시간째<span>-----28%</span></strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p></td></tr> <tr> <td width="615" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: windowtext 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 461.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ddd9c3; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid; mso-background-themecolor: background2; mso-background-themeshade: 230" colspan="3"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>대상자<span>:<span> </span>2</span>형 당뇨병 자로서 관상 동맥 질환 지니자</strong></span></p> <p align="left" style="LINE-HEIGHT: normal; TEXT-INDENT: 40pt; MARGIN: 0cm 0cm 0pt; mso-char-indent-count: 4.0"><strong><span style="FONT-SIZE: 14pt; mso-bidi-font-family: AdvTTd310d995">염증 지수<span>(hsCRP </span>높은지 혈소판 수 높은지 끽연 자</span></strong></p></td></tr> <tr style="mso-yfti-irow: 5; mso-yfti-lastrow: yes"> <td width="615" style="BORDER-BOTTOM: windowtext 1pt solid; BORDER-LEFT: windowtext 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 461.2pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ffccff; BORDER-TOP: #ece9d8; BORDER-RIGHT: windowtext 1pt solid" colspan="3"> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="FONT-SIZE: 14pt">Apsirin</span><span style="FONT-SIZE: 14pt">은 장용정이 아닌<span> Aspriin lysinate </span>분말을 사용</span></strong></p></td></tr></tbody></table> <p style="MARGIN: 0cm 0cm 10pt"><span><strong></strong></span> </p> <p style="MARGIN: 0cm 0cm 10pt"><span><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong></strong></span> </p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span><strong></strong></span> </p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: black; FONT-SIZE: 14pt"></span></p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"></span></strong> </p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"><img width="702" height="245" style="WIDTH: 700px; HEIGHT: 289px" src="/_dimg/5%20cox.bmp"></span></strong></p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">[</span><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">그림<span>] </span>아스피린은 소량만으로 모든 혈소판 속에 있는</span></strong><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"> Cox-1 </span><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">과 결합하며 남는 아스피린 량은 </span></strong></p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"> 즉시 </span></strong><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">세칠기가 없어진<span> Salicylic Acid </span>가 되어</span></strong><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"> </span><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">혈전 억제는 못하지만 항염 작용은 발휘할</span></strong></p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"> 수 있다 </span></strong><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">혈전 유발 불<span>Thromboxane A2</span>는 일종의 푸로스타그란딘이며</span></strong><strong><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"> </span><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold">혈소판속의 효소<span> </span></span></strong></p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span><strong><span> <font size="4"> <font color="#ff0000">Cox-1 </font></font></span><font size="4"><font color="#ff0000">이 만들어내어 필요할 때</font> </font></strong></span><font size="4"><span style="COLOR: red; FONT-SIZE: 14pt; mso-bidi-font-weight: bold"><strong>혈소판을 응</strong><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-ascii-font-family: 굴림; mso-hansi-font-family: 굴림">집 </span><strong>시킨다</strong></span></font></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong><font size="4"></font></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: #3333ff; FONT-SIZE: 20pt"></span></strong> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: #3333ff; FONT-SIZE: 20pt">1</span><span style="COLOR: #3333ff; FONT-SIZE: 20pt">일<span> 1</span>회 복용이 </span></strong><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong>아스피린 효과 상실하는 이유</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 20pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>아스피린은 복용 후<span> 30-45</span>분에 최고 혈중 농도에 도달하며</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>아세칠기가 붙은 아스피린 자체의 반감기는 불과<span> 15</span>분<span>-20</span>분이다</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong> 아세칠기가 분리된 후 살리칠산의 반감기는 <span>5</span>시간 정도이지만</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>살리칠산은 항 혈소판 작용이 없다</strong></span></p> <p style="MARGIN: 0cm 0cm 10pt"><span style="LINE-HEIGHT: 115%; FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="MARGIN: 0cm 0cm 10pt"><span style="LINE-HEIGHT: 115%; FONT-SIZE: 14pt"><strong>따라서 아스피린이 혈액 중에서 혈소판을 포화시켜 </strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>항 혈소판 작용을 발휘하는 시간은 불과 <span> 2</span>시간 정도이다</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>또한 정상인의 경우는 </strong></span><span style="FONT-SIZE: 14pt"><strong>혈소판은 하루에<span> 10%-15% </span>가 없어지고</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>새로운 혈소판이 하루에<span> 10%-15% </span>가 생성 된다</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>이 정도의<span><span> </span></span>새로운 혈소판 농도로서는 </strong></span><span style="FONT-SIZE: 14pt"><strong>혈전 을 유발 할 수 없는 수준이다 </strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>아스피린이 결합 안된 새로운 혈소판이 적어도 </strong></span><strong><span style="FONT-SIZE: 14pt">20%-30%</span><span style="FONT-SIZE: 14pt">가 있어야 혈전 유발 농도가 된다</span></strong></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>그러나<span> 2</span>형 당뇨병자가 관상 동맥 질환을 지녔울 때는</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>본 임상결과 나타난 비와 같이 </strong></span><span style="FONT-SIZE: 14pt"><strong>혈소판 생성 율이 매우 높아진다는 사실이 밝혀진 것이다</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 20pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 20pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 20pt"><img width="551" height="187" style="WIDTH: 692px; HEIGHT: 367px" src="/_dimg/10%20Clopidogrel.jpg"></span></p><span style="COLOR: #3333ff; FONT-SIZE: 20pt"> <p style="MARGIN: 0cm 0cm 0pt"><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림">[</font></span><strong><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-ascii-font-family: 굴림; mso-hansi-font-family: 굴림">그림</span><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림">] </font></span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-ascii-font-family: 굴림; mso-hansi-font-family: 굴림">아스피린</span><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림"> </font></span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-ascii-font-family: 굴림; mso-hansi-font-family: 굴림">과</span><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림"> Clopidogrel</font></span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-ascii-font-family: 굴림; mso-hansi-font-family: 굴림">은</span><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림"> </font></span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-ascii-font-family: 굴림; mso-hansi-font-family: 굴림">각각</span><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림"> </font></span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-ascii-font-family: 굴림; mso-hansi-font-family: 굴림">혈소판의</span><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림">. </font></span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-ascii-font-family: 굴림; mso-hansi-font-family: 굴림">다른</span><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림"> </font></span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-ascii-font-family: 굴림; mso-hansi-font-family: 굴림">위치에서</span><span style="COLOR: red; FONT-SIZE: 14pt"></span></strong></p> <p style="TEXT-INDENT: 70pt; MARGIN: 0cm 0cm 0pt; mso-char-indent-count: 5.0"><strong><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-ascii-font-family: 굴림; mso-hansi-font-family: 굴림">응집</span><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림"> </font></span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-ascii-font-family: 굴림; mso-hansi-font-family: 굴림">력을</span><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림"> </font></span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-ascii-font-family: 굴림; mso-hansi-font-family: 굴림">파괴한다</span><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림"> </font></span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-ascii-font-family: 굴림; mso-hansi-font-family: 굴림">그러나</span><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림"> </font></span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-ascii-font-family: 굴림; mso-hansi-font-family: 굴림">아스피린이</span><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림"> </font></span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-ascii-font-family: 굴림; mso-hansi-font-family: 굴림">더광범위한</span><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림"> </font></span></strong></p> <p style="TEXT-INDENT: 70pt; MARGIN: 0cm 0cm 0pt; mso-char-indent-count: 5.0"><strong><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-ascii-font-family: 굴림; mso-hansi-font-family: 굴림">혈소판</span><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림"> </font></span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-ascii-font-family: 굴림; mso-hansi-font-family: 굴림">억제력을</span><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림"> </font></span><span style="FONT-FAMILY: '맑은 고딕'; COLOR: red; FONT-SIZE: 14pt; mso-ascii-font-family: 굴림; mso-hansi-font-family: 굴림">나타낸다</span><span style="COLOR: red; FONT-SIZE: 14pt"></span></strong></p> <p style="TEXT-INDENT: 70pt; MARGIN: 0cm 0cm 0pt; mso-char-indent-count: 5.0"><span style="COLOR: red; FONT-SIZE: 14pt"><font face="굴림"></font></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: #3333ff; FONT-SIZE: 20pt"></span></strong> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: #3333ff; FONT-SIZE: 20pt"></span></strong> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="COLOR: #3333ff; FONT-SIZE: 20pt">Clopidogrel </span><span style="COLOR: #3333ff; FONT-SIZE: 20pt">은 </span></strong><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong>아스피린 복용 법에 영향을 미치지 않는다</strong></span></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="COLOR: #3333ff; FONT-SIZE: 20pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong>본 임상에서 <span>57</span>명이 아스피린<span> 1</span>일<span> 2</span>회 요법에 </strong></span><strong><span style="FONT-SIZE: 14pt">Clopidogrel 1</span><span style="FONT-SIZE: 14pt">일<span> 1</span>회 요법을 병용한 자들이다</span></strong></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><span style="FONT-SIZE: 14pt"><strong></strong></span> </p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt; BACKGROUND: white"><strong><span style="FONT-SIZE: 14pt">[</span><span style="FONT-SIZE: 14pt">근거<span>]</span></span></strong></p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt; BACKGROUND: white"><span><a title="American heart journal." href="http://www.ncbi.nlm.nih.gov/pubmed/23067920"><span style="COLOR: #2f4a8b; FONT-SIZE: 14pt"><strong>Am Heart J.</strong></span></a></span><strong><span style="FONT-SIZE: 14pt"> 2012 Oct;164(4):600-606.e1. doi: </span><span style="FONT-SIZE: 14pt; mso-bidi-font-family: 'AdvTTdd02cf66.B'"></span></strong></p> <p align="left" style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"><strong><span style="FONT-SIZE: 14pt; mso-bidi-font-family: 'AdvTTdd02cf66.B'">Biological efficacy of twice daily aspirin in type 2 diabetic patients with coronary artery disease; </span><span style="FONT-SIZE: 14pt; mso-bidi-font-family: 'AdvTT7ba55b3c.B'">Jean-Guillaume Dillinger, MD, a,c Akram Drissa, MD, a,c Georgios Sideris, MD, a Claire Bal dit Sollier, PhD, b Sebastian Voicu, MD, a Stephane Manzo Silberman, MD, a Damien Logeart, MD, a Ludovic Drouet, MD, PhD, b and Patrick Henry, MD, PhD a </span><span style="FONT-SIZE: 14pt; mso-bidi-font-family: 'AdvTT010224ac.BI'">Paris, France. </span><span style="FONT-SIZE: 14pt">Cardiology-Lariboisiere Hospital, AP-HP-Paris Diderot University, INSERM U942, Paris, France.</span></strong></p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"> </p> <p style="LINE-HEIGHT: normal; MARGIN: 0cm 0cm 0pt"> </p></span></span></span> 이전글다음글 목록
