경년기 이후 여성 질환 예방 용 여성 호르몬 요법 안정 성 평가 최종 결과 -미국 정부 지원 여성 건강 향상 계획 WHI임상- > 복약 지도

경년기 이후 여성 질환 예방 용 여성 호르몬 요법 안정 성 평가 최종 결과 -미국 정부 지원 여성 건강 향상 계획 WHI임상-

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경년기 이후 여성 질환 예방 용 여성 호르몬 요법
 
안정 성 평가 최종 결과 발표
 
-미국 정부 지원 여성 건강 향상 계획 WHI 임상-
 
 
작열 감 같은 여성 갱년 기 증후 군을 예방하거나 
심장 병 과 유방 암 같은 만성 질환을 예방 하기 위하여 
반 세;기를 통해 처방 되어 온 
갱년기 이후 여성 호르몬 요법(HRT)에 대하여 
무려 16만 명을 대상으로 한 20년간의 최종 임상 결과가 
마침내 미국 의사 회 학술 지(JAMA)를 통해 발표되었다
 
이는 여성 건강 향상을 위해 미국 정부로 부터 100% 지원 받기 시작한 
최초의 대 단위 임상이며 미국 보건성의 책임하에 실시된
역사적 임상이기도 하다
 
 
 
 
 
<IMG style="WIDTH: 514px; HEIGHT: 432px" src="/_dimg/4-1%2020150526_184607.png" width=512 height=227>
 
 
대부분의 중요 질환에 대하여 발병을 촉진 
 
장기 요법 제로 사용하면 위험하다
 
갱년기 장애를 예방 하기 위하여 또는 갱년기 이후 만성 질환 발생을 
예방하기 위하여 자궁 절제 자에게는 Estrogen 단일 제제를 사용해왔다
 
또한 자궁 절제를 안 한 여인들에게는  Estrogen 과 Progesterone 복합 제를 
사용 해 왔다 Progesterone 을 추가하는 이유는 자궁 내막 암을 방지 
하기 위해서다 
 
그러나 복합 제 요법이든 단일 제 요법이던 간에
아래 표에 나타나있는 바와 같이
중대한 만성 질환들에 대하여 Placebo군 보다 오히려 발병 율이 놓다
 
작열 감 같은 갱년기 증상에는 효과가 인정된다 할지라도 만성 질환 예방 용으로는 득보다는 해롭다는 사실이 입증된 것이다
 
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1993년-1998 시작
2010년 9월 30일 종료
 
(임상 기간=13년)</TD>
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Placebo군 대비 발병 비교 위험 도 (Hazard Ratio) 
(해설: 1 이상은 발병 촉진  1 이하는 예방 효과 </TD></TR>
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자궁 절제 인한 여인 </TD>
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자궁 절제한 여인 </TD></TR>
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Estrogen+ Progesterone 군 8,506명
Placebo 군 8,102명</TD>
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Estrogen 군 5,310명
Placebo  군 5,429명</TD></TR>
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년령 층 </TD>
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50-59세</TD>
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60-69세</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #eeece1; HEIGHT: 22.05pt; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; mso-background-themecolor: background2" width=76>
70-79세</TD>
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50-59세</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #eeece1; HEIGHT: 22.05pt; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; mso-background-themecolor: background2" width=76>
60-69세</TD>
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70-79세</TD></TR>
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관상 동맥 질환</TD>
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1.34</TD>
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1.01</TD>
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1.31</TD>
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0.60</TD>
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0.95</TD>
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1.07</TD></TR>
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유방 암 </TD>
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1.21</TD>
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1.20</TD>
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1.37</TD>
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0.82</TD>
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0.73</TD>
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0.86</TD></TR>
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뇌졸중 </TD>
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1.51</TD>
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1.45</TD>
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1.22</TD>
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0.99</TD>
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1.55</TD>
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1.29</TD></TR>
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폐색전</TD>
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2.05</TD>
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1.69</TD>
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2.54</TD>
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1.53</TD>
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1.72</TD>
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0.85</TD></TR>
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대장 암</TD>
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0.79</TD>
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0.51</TD>
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0.58</TD>
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0.71</TD>
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0.88</TD>
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2.24</TD></TR>
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자궁 내막 암 </TD>
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1.07</TD>
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0.76</TD>
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0.85</TD>
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해당 무</TD>
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해당 무</TD>
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해당 무</TD></TR>
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하프 골절</TD>
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0.17</TD>
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0.76</TD>
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0.58</TD>
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5.10</TD>
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0.47</TD>
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0.65</TD></TR>
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모든 원인의 사망</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
0.67</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
1.07</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
1.03</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
0.70</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
1.01</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
1.21</TD></TR>
<TR >
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 97.55pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=130>
모든 원인의 
심근 경색</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
1,32</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
1.05</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
1.46</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
0.55</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
0.95</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
1.24</TD></TR>
<TR >
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 97.55pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=130>
심장 수술</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
1.03</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
0.85</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
1.08</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
0.56</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
1.13</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
1.07</TD></TR>
<TR >
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 97.55pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=130>
모든 종류의 암</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
0.97</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
1.11</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
0.94</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
0.89</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
0.89</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 2cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=76>
1.04</TD></TR>
<TR style="mso-yfti-irow: 15; mso-yfti-lastrow: yes">
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 437.75pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #f2f2f2; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=584 colSpan=7>
Estrogen= Conjugated Equine Estrogen 0.625mg/day
Progensterone=Medroxyprogesterone acetate 2.5mg/day
본 임상은 무 작위 엄격한 통제 하의 비교 임상으로 도합 27,357명이 참여 했으며
통제 없이 실시한 관찰적 임상은 무려 93,676명에 대하여 8년간 관찰했다</TD></TR></TBODY></TABLE>
 
 
 

<TABLE style="WIDTH: 402.3pt; BORDER-COLLAPSE: collapse; mso-yfti-tbllook: 1184; mso-padding-alt: 0cm 5.4pt 0cm 5.4pt" Table border=0 cellSpacing=0 cellPadding=0 width=536>
<TBODY>
<TR style="mso-yfti-irow: 0; mso-yfti-firstrow: yes">
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 104.65pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid; " rowSpan=3 width=140>
1993년-1998 시작
2002-2004 종료
(임상 기간=5.6)</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 297.65pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ffff; BORDER-TOP: black 1pt solid; BORDER-RIGHT: black 1pt solid; " width=397 colSpan=2>
Placebo군 대비 발병 비교 위험 도 (Hazard Ratio) 
(해설: 1 이상은 발병 촉진  1 이하는 예방 효과 </TD></TR>
<TR >
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 5cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=189>
자궁 절제 인한 여인</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #ccffff; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=208>
자궁 절제한 여인</TD></TR>
<TR >
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 5cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=189>
Estrogen+ Progesterone 군 8,506명
Placebo 군 8,102명</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #fde9d9; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=208>
Estrogen 군 5,310명
Placebo  군 5,429명</TD></TR>
<TR >
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 104.65pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=140>
심부 정맥 혈전 증 </TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 5cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=189>
1.87</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=208>
1.48</TD></TR>
<TR >
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 104.65pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=140>
폐 암 </TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 5cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=189>
1.05</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=208>
1.05</TD></TR>
<TR >
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 104.65pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=140>
난소 암 </TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 5cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=189>
1.41</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=208>
해당 무</TD></TR>
<TR >
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 104.65pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=140>
척추 골절 </TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 5cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=189>
0.68</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=208>
0.64</TD></TR>
<TR >
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 104.65pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=140>
모든 골절</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 5cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=189>
0.76</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=208>
0.72</TD></TR>
<TR >
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 104.65pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=140>
치매 증 가능성</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 5cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=189>
2.01</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=208>
1.47</TD></TR>
<TR >
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 104.65pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=140>
당뇨병</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 5cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=189>
0.81</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=208>
0.86</TD></TR>
<TR >
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 104.65pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=140>
담석 증</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 5cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=189>
1.57</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=208>
1.55</TD></TR>
<TR >
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 104.65pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=140>
요 실금</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 5cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=189>
1.49</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=208>
1.61</TD></TR>
<TR >
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 104.65pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=140>
작열 감</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 5cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=189>
0.36</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=208>
0.72</TD></TR>
<TR >
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 104.65pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=140>
유방 통증</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 5cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=189>
3.93</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=208>
2.48</TD></TR>
<TR >
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 104.65pt; PADDING-RIGHT: 5.4pt; BACKGROUND: yellow; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=140>
관절 통</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 5cm; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=189>
0.72</TD>
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: #ece9d8; PADDING-LEFT: 5.4pt; WIDTH: 155.9pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #66ff66; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=208>
0.91</TD></TR>
<TR style="mso-yfti-irow: 15; mso-yfti-lastrow: yes">
<TD style="BORDER-BOTTOM: black 1pt solid; BORDER-LEFT: black 1pt solid; PADDING-LEFT: 5.4pt; WIDTH: 402.3pt; PADDING-RIGHT: 5.4pt; BACKGROUND: #f2f2f2; BORDER-TOP: #ece9d8; BORDER-RIGHT: black 1pt solid; " width=536 colSpan=3>
본 표에는 13년 임상 결과 표 에 포함된 질환은 제외 됨
Estrogen= Conjugated Equine Estrogen 0.625mg/day
Progensterone=Medroxyprogesterone acetate 2.5mg/day
본 임상은 무 작위 엄격한 통제 하의 비교 임상으로 도합 27,357명이 참여 했으며
통제 없이 실시한 관찰적 임상은 무려 93,676명에 대하여 8년 간 관찰했다</TD></TR></TBODY></TABLE>
 
 
 
 
 

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여성 건강 향상 계획 WHI 란 
 
여성 건강 향상 계획(Women’s Health Initiative이란 
1991년 미국 정부 보건 성 장관이며 의사인